SCHEMBL140532

SCHEMBL140532

OC(O)CCCCCSCCCCCC(O)O

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
BHMT Q93088 3/20 0.36
CES2 O00748 3/20 0.34
GMNN O75496 1/20 0.34
TP53 P04637 1/20 0.34
POLB P06746 1/20 0.34
MAPT P10636 1/20 0.34
THRB P10828 1/20 0.34
CYP2C9 P11712 1/20 0.34
BLM P54132 1/20 0.34
HSD17B10 Q99714 1/20 0.34
TRPV1 Q8NER1 1/20 0.31
TRPA1 O75762 1/20 0.31
FAAH O00519 4/20 0.30
CES1 P23141 4/20 0.30
PLA2G6 O60733 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28366942 1.00 BHMT (0.36) BHMTCES2GMNNTP53POLB
SCHEMBL31520214 1.00 BHMT (0.36) BHMTCES2GMNNTP53POLB
SCHEMBL8578846 0.88 TDP1 (0.32) BHMT
SCHEMBL20916744 0.82 FOLH1 (0.32) TRPV1TRPA1
SCHEMBL20916752 0.82 FOLH1 (0.32) TRPV1TRPA1
SCHEMBL31520215 0.82 FOLH1 (0.32) TRPV1TRPA1
SCHEMBL541720 0.80 TRPV1 (0.40) GMNNTP53POLBMAPTBLM
SCHEMBL21624976 0.80 TRPV1 (0.40) GMNNTP53POLBMAPTBLM
SCHEMBL8735841 0.80 TRPV1 (0.40) GMNNTP53POLBMAPTBLM
SCHEMBL8777953 0.80 TRPV1 (0.40) GMNNTP53POLBMAPTBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11560445-B2 Silylated polyurethanes and methods for preparing thereof HENKEL AG & CO. KGAA (DE) 2023-01-24 US disclosed
EP-3498748-B1 SILYLATED POLYURETHANES AND METHODS FOR PREPARING THEREOF HENKEL AG & CO KGAA (DE) 2022-02-02 EP disclosed
US-11078323-B2 Silane coupling agents HENKEL AG & CO. KGAA (DE) 2021-08-03 US disclosed
EP-3655452-B1 SILYLATED POLYURETHANES AND METHODS FOR PREPARING THEREOF HENKEL AG & CO KGAA (DE) 2021-07-07 EP disclosed
US-10889682-B2 Silylated polyurethanes and methods for preparing thereof HENKEL AG & CO. KGAA (DE) 2021-01-12 US disclosed
US-20200299450-A1 Silylated Polyurethanes and Methods for Preparing Thereof HENKEL AG & CO. KGAA (DE) 2020-09-24 US disclosed
EP-3655452-A1 SILYLATED POLYURETHANES AND METHODS FOR PREPARING THEREOF Henkel AG & Co. KGaA (DE) 2020-05-27 EP disclosed
US-20200148808-A1 Silylated Polyurethanes and Methods for Preparing Thereof HENKEL AG & CO. KGAA (DE) 2020-05-14 US disclosed
EP-3395847-B1 SILANE COUPLING AGENTS HENKEL AG & CO KGAA (DE) 2020-03-11 EP disclosed
US-20200048406-A1 Silane Coupling Agents HENKEL AG & CO. KGAA (DE) 2020-02-13 US disclosed
EP-3395847-A1 SILANE COUPLING AGENTS Henkel AG & Co. KGaA (DE) 2018-10-31 EP disclosed
US-8609800-B2 Curable compositions containing silylated polyurethanes HENKEL AG & CO. KGAA (DE) 2013-12-17 US disclosed
US-20130280530-A1 TWO-COMPONENT CURABLE COMPOSITION HENKEL AG & CO KGAA (DE) 2013-10-24 US disclosed
US-8563675-B2 Curable compositions composed of silanes with two hydrolyzable groups HENKEL AG & CO. KGAA (DE) 2013-10-22 US disclosed
US-20130274414-A1 CURABLE COMPOSITION HAVING A SPECIAL CATALYST/SOFTNER SYSTEM HENKEL AG & CO. KGAA (DE) 2013-10-17 US disclosed
US-20120055105-A1 ADHESIVES AND SEALANTS BASED ON SILANE-TERMINATED BINDERS FOR BONDING AND SEALING FLEXIBLE SOLAR FILMS/PHOTOVOLTAIC MODULES HENKEL AG & CO. KGAA (DE) 2012-03-08 US disclosed
US-20110071254-A1 CURABLE COMPOSITIONS CONTAINING SILYLATED POLYETHER BLOCK POLYMER-BASED POLYURETHANES HENKEL AG & CO. KGAA (DE) 2011-03-24 US disclosed
US-20110034627-A1 CURABLE COMPOSITIONS CONTAINING SILYLATED POLYURETHANES HENKEL AG & CO. KGAA (DE) 2011-02-10 US disclosed
US-20100204387-A1 CURABLE COMPOSITIONS COMPOSED OF SILANES WITH TWO HYDROLYZABLE GROUPS HENKEL AG & CO. KGAA (DE) 2010-08-12 US disclosed
US-20100143712-A1 SILANE-CROSSLINKING ADHESIVE OR SEALANT COMPRISING N-SILYLALKYLAMIDES AND USE THEREOF HENKEL AG & CO. KGAA (DE) 2010-06-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11078323-B2 Silane coupling agents MACF1, SEPTIN8, ICAM1 BHMT 1685/4885CES2 2173/4885GMNN 288/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.