SCHEMBL1405359

SCHEMBL1405359

Cc1cccc(/C=C/c2ccccc2)c1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RELA Q04206 2/20 0.66
ALOX5 P09917 2/20 0.62
PTGS1 P23219 2/20 0.62
PTGS2 P35354 2/20 0.62
TP53 P04637 1/20 0.58
TDP1 Q9NUW8 1/20 0.58
NPC1 O15118 3/20 0.56
NFE2L2 Q16236 2/20 0.56
MAOA P21397 2/20 0.56
MAOB P27338 2/20 0.56
CASP3 P42574 2/20 0.56
SENP8 Q96LD8 2/20 0.56
SENP7 Q9BQF6 2/20 0.56
SENP6 Q9GZR1 2/20 0.56
CYP19A1 P11511 1/20 0.56
FBP1 P09467 1/20 0.55
TTR P02766 1/20 0.52
ALDH1A1 P00352 3/20 0.51
LMNA P02545 2/20 0.51
GAA P10253 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16105781 1.00 RELA (0.66) RELAALOX5PTGS1PTGS2TP53
SCHEMBL318044 1.00 RELA (0.66) RELAALOX5PTGS1PTGS2TP53
SCHEMBL29446273 1.00 RELA (0.66) RELAALOX5PTGS1PTGS2TP53
SCHEMBL1179749 0.93 RELA (0.74) RELAALOX5PTGS1PTGS2TP53
SCHEMBL29673932 0.93 RELA (0.74) RELAALOX5PTGS1PTGS2TP53
SCHEMBL1179750 0.93 RELA (0.74) RELAALOX5PTGS1PTGS2TP53
SCHEMBL1795132 0.93 PTGS1 (0.69) RELAALOX5PTGS1PTGS2TP53
SCHEMBL21847980 0.93 PTGS1 (0.69) RELAALOX5PTGS1PTGS2TP53
SCHEMBL1795130 0.93 PTGS1 (0.69) RELAALOX5PTGS1PTGS2TP53
SCHEMBL23458000 0.91 MAOB (0.61) RELAALOX5PTGS1PTGS2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12404221-B2 Methods of arene alkenylation UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2025-09-02 US disclosed
CN-118032697-A Universal analysis method for fluorescent whitening agent structure analysis 上海新泊地化工技术服务有限公司 2024-05-14 CN disclosed
US-20230234900-A1 METHODS OF ARENE ALKENYLATION UNIVERSITY OF VIRGINIA PATENT FOUNDATION 2023-07-27 US disclosed
CN-114195610-B Synthesis method of E-type internal olefin compound 海南大学 2023-07-14 CN disclosed
CN-114195610-A Synthetic method of E-type internal olefin compound 海南大学 2022-03-18 CN disclosed
WO-2021074275-A1 EFFECTIVE PHOTOMODULATION OF LANTHANIDE (III) ION LUMINESCENCE IN THE VISIBLE OR NEAR-INFRARED RANGE UNIVERSITE DE RENNES 1 (FR) 2021-04-22 WO disclosed
CN-108658718-B Preparation method of trans-stilbene compound 温州大学 2020-12-18 CN disclosed
CN-108658718-A A kind of preparation method of trans-stilbene compounds 温州大学 2018-10-16 CN disclosed
US-20180223181-A1 SILOXANE MONOMER, POLYMER THEREOF, COMPOSITION CONTAINING SAID POLYMER, AND ELECTRONIC ELEMENT DAINIPPON INK & CHEMICALS (JP) 2018-08-09 US disclosed
US-9925153-B2 Therapeutic agents for skin diseases and conditions STC.UNM (US) 2018-03-27 US disclosed
EP-1591830-A2 Reimageable medium Xerox Corporation (US) 2005-11-02 EP disclosed
EP-0903965-B1 MULTICOLOR ORGANIC EL ELEMENT, METHOD FOR MANUFACTURING THE SAME, AND DISPLAY USING THE SAME CHEMIPRO KASEI KAISHA LTD (JP) 2003-07-30 EP disclosed
EP-1011155-B1 Organic electroluminescent device KIDO JUNJI (JP) 2003-06-04 EP disclosed
US-20030057827-A1 Multicolor organic element, method for manufacturing the same, and display using the same CHEMIPRO KASEI KAISHA, LIMITED (JP) 2003-03-27 US disclosed
EP-0903965-A1 MULTICOLOR ORGANIC EL ELEMENT, METHOD FOR MANUFACTURING THE SAME, AND DISPLAY USING THE SAME CHEMIPRO KASEI KAISHA, LIMITED (JP) 1999-03-24 EP disclosed
US-5759729-A A DRY TONER COMPRISING A RESIN, PHOTOCHROMATIC SPIROPYRAN, -OXAZINE OR -THIOPYRAN DYE AND A CHARGE CONTROL AGENT;ELECTROGRAPHY; XEROGRAPHY XEROX CORPORATION (US) 1998-06-02 US disclosed
US-5710420-A Method for embedding and recovering machine-readable information XEROX CORPORATION (US) 1998-01-20 US disclosed
US-5633109-A Ink compositions with liposomes containing photochromic compounds XEROX CORPORATION (US) 1997-05-27 US disclosed
US-5593486-A Photochromic hot melt ink compositions XEROX CORPORATION (US) 1997-01-14 US disclosed
US-5551973-A LIQUID CRYSTAL GEL PHASE, MICROEMULSION PHASE XEROX CORPORATION (US) 1996-09-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180223181-A1 SILOXANE MONOMER, POLYMER THEREOF, COMPOSITION CONTAINING SAID POLYMER, AND ELECTRONIC ELEMENT ILK, LIMA1, EED RELA 4189/4885ALOX5 670/4885PTGS1 2444/4885
US-20230234900-A1 METHODS OF ARENE ALKENYLATION CYBB, CBR3, AHR RELA 732/4885ALOX5 117/4885PTGS1 2007/4885
US-12404221-B2 Methods of arene alkenylation CYBB, CBR3, AHR RELA 732/4885ALOX5 117/4885PTGS1 2007/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.