Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 2/20 | 0.40 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | PI4KA | P42356 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31372462 | 0.84 | NISCH (0.48) | PIM1NISCHMETAP2HSP90AA1CYP1A2 | |
| SCHEMBL78566 | 0.82 | NISCH (0.50) | PIM1NISCHMETAP2HSP90AA1CYP1A2 | |
| SCHEMBL29598957 | 0.82 | NISCH (0.50) | PIM1NISCHMETAP2HSP90AA1CYP1A2 | |
| SCHEMBL29454745 | 0.82 | NISCH (0.50) | PIM1NISCHMETAP2HSP90AA1CYP1A2 | |
| SCHEMBL14053846 | 0.79 | NISCH (0.48) | PIM1NISCHMETAP2HSP90AA1CYP1A2 | |
| Hydrochloric Acid SCHEMBL3640139 | 0.79 | NISCH (0.48) | PIM1NISCHMETAP2HSP90AA1CYP1A2 | |
| SCHEMBL9794662 | 0.79 | NISCH (0.48) | PIM1NISCHMETAP2HSP90AA1CYP1A2 | |
| Hydrochloric Acid SCHEMBL30272980 | 0.76 | NISCH (0.46) | PIM1NISCHMETAP2HSP90AA1CYP1A2 | |
| SCHEMBL29713632 | 0.75 | NISCH (0.42) | PIM1NISCHMETAP2HSP90AA1CYP1A2 | |
| SCHEMBL29712763 | 0.73 | CYP11B1 (0.44) | PIM1NISCHMETAP2HSP90AA1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8778988-B2 | Endoperoxides and methods of photocatalytically synthesizing endoperoxides | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2014-07-15 | — | — | US | claimed |
| US-20120302523-A1 | ENDOPEROXIDES AND METHODS OF PHOTOCATALYTICALLY SYNTHESIZING ENDOPEROXIDES | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2012-11-29 | — | — | US | claimed |
| US-8778988-B2 | Endoperoxides and methods of photocatalytically synthesizing endoperoxides | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2014-07-15 | — | — | US | disclosed |
| US-20120302523-A1 | ENDOPEROXIDES AND METHODS OF PHOTOCATALYTICALLY SYNTHESIZING ENDOPEROXIDES | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2012-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120302523-A1 | ENDOPEROXIDES AND METHODS OF PHOTOCATALYTICALLY SYNTHESIZING ENDOPEROXIDES | QSOX1, GPX4, PRDX2 | PIM1 4026/4885NISCH 706/4885METAP2 1474/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.