SCHEMBL1405644

SCHEMBL1405644

O=C(c1ccccc1)c1ccc(C=Cc2ccccc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 2/20 0.64
ALDH1A1 P00352 2/20 0.64
SRD5A2 P31213 2/20 0.60
MAPT P10636 4/20 0.57
LMNA P02545 3/20 0.57
PLIN1 O60240 2/20 0.57
RECQL P46063 2/20 0.57
PLIN5 Q00G26 2/20 0.57
ABHD5 Q8WTS1 2/20 0.57
MAOB P27338 2/20 0.57
CYP1B1 Q16678 2/20 0.57
BCHE P06276 1/20 0.57
TNFRSF1A P19438 1/20 0.57
ACHE P22303 1/20 0.57
TDP1 Q9NUW8 2/20 0.54
CHEK1 O14757 1/20 0.54
KDR P35968 1/20 0.54
ATM Q13315 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
F3 P13726 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1405641 1.00 HDAC1 (0.64) HDAC1ALDH1A1SRD5A2MAPTLMNA
SCHEMBL15768763 0.98 ALDH1A1 (0.67) HDAC1ALDH1A1SRD5A2MAPTLMNA
SCHEMBL15768764 0.98 ALDH1A1 (0.67) HDAC1ALDH1A1SRD5A2MAPTLMNA
SCHEMBL27792692 0.98 HDAC1 (0.67) HDAC1ALDH1A1SRD5A2MAPTLMNA
(Z)-1,2-Diphenylethene SCHEMBL27764636 0.95 ALDH1A1 (0.70) HDAC1ALDH1A1SRD5A2MAPTLMNA
SCHEMBL15769072 0.91 SRD5A2 (0.75) HDAC1ALDH1A1SRD5A2TDP1ATM
SCHEMBL15769075 0.91 SRD5A2 (0.75) HDAC1ALDH1A1SRD5A2TDP1ATM
Phosphonic Acid SCHEMBL15768787 0.90 ALDH1A1 (0.56) HDAC1ALDH1A1SRD5A2MAPTLMNA
Phosphonic Acid SCHEMBL15768785 0.90 ALDH1A1 (0.56) HDAC1ALDH1A1SRD5A2MAPTLMNA
SCHEMBL15784122 0.88 KMT2A (0.54) HDAC1ALDH1A1SRD5A2MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9868873-B2 Photochromic security enabled ink for digital offset printing applications XEROX CORPORATION (US) 2018-01-16 US disclosed
US-20130305947-A1 PHOTOCHROMIC SECURITY ENABLED INK FOR DIGITAL OFFSET PRINTING APPLICATIONS XEROX CORPORATION (US) 2013-11-21 US disclosed
EP-1591830-B1 Reimageable medium XEROX CORP (US) 2011-03-09 EP disclosed
US-20100302927-A1 OPTICAL DATA STORAGE MEDIUM AND METHODS FOR USING THE SAME GENERAL ELECTRIC COMPANY (US) 2010-12-02 US disclosed
US-7556844-B2 Radiation curable photochromic inks XEROX CORPORATION (US) 2009-07-07 US disclosed
US-7521159-B2 Multicolor electronic paper XEROX CORPORATION (US) 2009-04-21 US disclosed
US-7300727-B2 Method for forming temporary image XEROX CORPORATION (US) 2007-11-27 US disclosed
US-20070211110-A1 RADIATION CURABLE PHOTOCHROMIC INKS XEROX CORPORATION (US) 2007-09-13 US disclosed
US-7214456-B2 Reimageable medium XEROX CORPORATION (US) 2007-05-08 US disclosed
US-7205088-B2 Reimageable medium with light absorbing material XEROX CORPORATION (US) 2007-04-17 US disclosed
US-20050244744-A1 Method for forming temporary image XEROX CORPORATION 2005-11-03 US disclosed
EP-1591830-A2 Reimageable medium Xerox Corporation (US) 2005-11-02 EP disclosed
EP-1591831-A2 Reimageable medium with light absorbing material Xerox Corporation (US) 2005-11-02 EP disclosed
EP-1591829-A1 Method for forming temporary image Xerox Corporation (US) 2005-11-02 EP disclosed
US-5759729-A A DRY TONER COMPRISING A RESIN, PHOTOCHROMATIC SPIROPYRAN, -OXAZINE OR -THIOPYRAN DYE AND A CHARGE CONTROL AGENT;ELECTROGRAPHY; XEROGRAPHY XEROX CORPORATION (US) 1998-06-02 US disclosed
US-5710420-A Method for embedding and recovering machine-readable information XEROX CORPORATION (US) 1998-01-20 US disclosed
US-5633109-A Ink compositions with liposomes containing photochromic compounds XEROX CORPORATION (US) 1997-05-27 US disclosed
US-5593486-A Photochromic hot melt ink compositions XEROX CORPORATION (US) 1997-01-14 US disclosed
US-5551973-A LIQUID CRYSTAL GEL PHASE, MICROEMULSION PHASE XEROX CORPORATION (US) 1996-09-03 US disclosed
WO-1993001173-A1 PRODUCTION OF AROMATIC OLEFINS YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 1993-01-21 WO disclosed