Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.47 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphonic Acid SCHEMBL15768785 | 1.00 | ALDH1A1 (0.56) | ALDH1A1SRD5A2HDAC1ATMTDP1 | |
| SCHEMBL15768764 | 0.92 | ALDH1A1 (0.67) | ALDH1A1SRD5A2HDAC1ATMTDP1 | |
| SCHEMBL15768763 | 0.92 | ALDH1A1 (0.67) | ALDH1A1SRD5A2HDAC1ATMTDP1 | |
| SCHEMBL1405641 | 0.90 | HDAC1 (0.64) | ALDH1A1SRD5A2HDAC1ATMTDP1 | |
| SCHEMBL1405644 | 0.90 | HDAC1 (0.64) | ALDH1A1SRD5A2HDAC1ATMTDP1 | |
| SCHEMBL27792692 | 0.87 | HDAC1 (0.67) | ALDH1A1SRD5A2HDAC1ATMTDP1 | |
| SCHEMBL15769072 | 0.86 | SRD5A2 (0.75) | ALDH1A1SRD5A2HDAC1ATMTDP1 | |
| SCHEMBL15769075 | 0.86 | SRD5A2 (0.75) | ALDH1A1SRD5A2HDAC1ATMTDP1 | |
| (Z)-1,2-Diphenylethene SCHEMBL27764636 | 0.85 | ALDH1A1 (0.70) | ALDH1A1SRD5A2HDAC1ATMTDP1 | |
| Benzophenone SCHEMBL27604696 | 0.85 | ALDH1A1 (0.78) | ALDH1A1SRD5A2ATMTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9629945-B2 | Stilbene-based reactive compounds, polymeric matrices formed therefrom, and articles visualizable by fluorescence | SURMODICS, INC. (US) | 2017-04-25 | — | — | US | disclosed |
| US-20140162083-A1 | STILBENE-BASED REACTIVE COMPOUNDS, POLYMERIC MATRICES FORMED THEREFROM, AND ARTICLES VISUALIZABLE BY FLUORESCENCE | SURMODICS, INC. (US) | 2014-06-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140162083-A1 | STILBENE-BASED REACTIVE COMPOUNDS, POLYMERIC MATRICES FORMED THEREFROM, AND ARTICLES VISUALIZABLE BY FLUORESCENCE | ITK, NOTUM, ITGAM | ALDH1A1 1967/4885SRD5A2 4160/4885HDAC1 879/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.