SCHEMBL1405705

SCHEMBL1405705

CN(C)c1ccc(C=Cc2ccc([N+](=O)[O-])cc2[N+](=O)[O-])cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 4/20 0.56
BACE1 P56817 3/20 0.55
MAPT P10636 5/20 0.55
ALDH1A1 P00352 3/20 0.55
TDP1 Q9NUW8 3/20 0.55
KMT2A Q03164 3/20 0.55
MAPK1 P28482 2/20 0.55
HTT P42858 1/20 0.55
INSR P06213 1/20 0.54
LMNA P02545 2/20 0.51
SMN1; SMN2 Q16637 2/20 0.51
CYP19A1 P11511 1/20 0.47
CYP1A2 P05177 1/20 0.47
CYP3A4 P08684 1/20 0.47
TSHR P16473 1/20 0.47
PHLPP2 Q6ZVD8 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
ACHE P22303 3/20 0.46
BCHE P06276 2/20 0.45
MEN1 O00255 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1405711 1.00 PTGS2 (0.56) PTGS2BACE1MAPTALDH1A1TDP1
SCHEMBL10137902 0.85 APP (0.55) PTGS2BACE1MAPTALDH1A1TDP1
SCHEMBL10137905 0.85 PTGS2 (0.54) PTGS2BACE1MAPTALDH1A1TDP1
SCHEMBL3248725 0.84 NFE2L2 (0.61) PTGS2MAPTALDH1A1TDP1KMT2A
SCHEMBL3248727 0.84 NFE2L2 (0.61) PTGS2MAPTALDH1A1TDP1KMT2A
SCHEMBL16141098 0.83 MAPT (0.66) PTGS2MAPTALDH1A1TDP1KMT2A
SCHEMBL531105 0.83 MAPT (0.66) PTGS2MAPTALDH1A1TDP1KMT2A
SCHEMBL531104 0.83 MAPT (0.66) PTGS2MAPTALDH1A1TDP1KMT2A
SCHEMBL10430144 0.82 PTGS2 (0.64) PTGS2BACE1MAPTCYP19A1ACHE
SCHEMBL10430142 0.82 PTGS2 (0.64) PTGS2BACE1MAPTCYP19A1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9164480-B2 Holographic data storage device and method of making GENERAL ELECTRIC COMPANY (US) 2015-10-20 US claimed
EP-1697936-B1 NOVEL OPTICAL STORAGE MATERIALS BASED ON NARROWBAND OPTICAL PROPERTIES GEN ELECTRIC (US) 2011-03-09 EP claimed
WO-2009148454-A1 METHOD OF MODIFYING A LENS SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2009-12-10 WO claimed
US-20080144146-A1 Holographic data storage device and method of making GENERAL ELECTRIC COMPANY 2008-06-19 US claimed
US-20080137032-A1 Optical lens and method of manufacturing GENERAL ELECTRIC COMPANY (US) 2008-06-12 US claimed
US-20070146835-A1 Methods for making holographic data storage articles GENERAL ELECTRIC COMPANY (US) 2007-06-28 US claimed
JP-2007514982-A 2007-06-07 JP claimed
WO-2007050354-A2 METHODS FOR MAKING HOLOGRAPHIC DATA STORAGE ARTICLES GENERAL ELECTRIC COMPANY (US) 2007-05-03 WO claimed
US-20070097469-A1 Methods for making holographic data storage articles GENERAL ELECTRIC COMPANY (US) 2007-05-03 US claimed
EP-1697936-A1 NOVEL OPTICAL STORAGE MATERIALS BASED ON NARROWBAND OPTICAL PROPERTIES GENERAL ELECTRIC COMPANY (US) 2006-09-06 EP claimed
WO-2005066949-A1 NOVEL OPTICAL STORAGE MATERIALS BASED ON NARROWBAND OPTICAL PROPERTIES GENERAL ELECTRIC COMPANY (A NEW YORK CORPORATION) (US) 2005-07-21 WO claimed
US-20050136333-A1 Novel optical storage materials based on narrowband optical properties GENERAL ELECTRIC COMPANY 2005-06-23 US claimed
CN-103430108-B Produce volume holographic pattern, shape or the method for image and the holographic article of generation thereof 沙特基础全球技术有限公司 2016-08-10 CN disclosed
US-9164480-B2 Holographic data storage device and method of making GENERAL ELECTRIC COMPANY (US) 2015-10-20 US disclosed
EP-2742389-A1 METHOD OF MAKING MULTIPLEXED TRANSMISSION HOLOGRAMS SABIC Innovative Plastics IP B.V. (NL) 2014-06-18 EP disclosed
EP-2726942-A2 HOLOGRAPHIC STORAGE METHOD AND ARTICLE SABIC Innovative Plastics IP B.V. (NL) 2014-05-07 EP disclosed
WO-2005051889-A1 M-DIAMINOBENZOLES AND THE ACIDIC ADDUCTS THEREOF AND USE THEREOF IN COLOURING AGENTS WELLA AKTIENGESELLSCHAFT (DE) 2005-06-09 WO disclosed
US-4740383-A COATING WITH COLOR-CHANGING SUBSTANCE FUJI PHOTO FILM CO., LTD. (JP) 1988-04-26 US disclosed
US-4004572-A Solar energy collection and retrieval employing reversible photochemical isomerization BATTELLE DEVELOPMENT CORPORATION (US) 1977-01-25 US disclosed
US-4004573-A Process and apparatus for solar energy collection and retrieval BATTELLE DEVELOPMENT CORPORATION (US) 1977-01-25 US disclosed