Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.40 |
| ▸ | TEK | Q02763 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12173602 | 1.00 | KIF11 (0.53) | KIF11TSHRDGAT1CA12CA9 | |
| SCHEMBL14327688 | 0.89 | KIF11 (0.38) | KIF11TSHRDGAT1NPC1RAB9A | |
| SCHEMBL25557807 | 0.85 | TSHR (0.41) | KIF11TSHRNPC1RAB9APIK3CD | |
| SCHEMBL10220397 | 0.83 | NPC1 (0.45) | KIF11CA12CA9NPC1RAB9A | |
| SCHEMBL701703 | 0.82 | TSHR (0.46) | KIF11TSHRDGAT1NPC1RAB9A | |
| SCHEMBL22601469 | 0.82 | GPR55 (0.40) | KIF11 | |
| SCHEMBL22601471 | 0.82 | KIF11 (0.55) | KIF11TSHRNPC1RAB9AALDH1A1 | |
| SCHEMBL22002106 | 0.81 | ALOX5AP (0.39) | KIF11TSHRDGAT1CA12CA9 | |
| SCHEMBL14327692 | 0.81 | ALOX5AP (0.39) | KIF11TSHRDGAT1CA12CA9 | |
| SCHEMBL15706254 | 0.80 | KIF11 (0.54) | KIF11ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7425281-B2 | Liquid crystal compositions comprising an organogermanium compound and methods for using the same | DISPLAYTECH, INC. (US) | 2008-09-16 | — | — | US | disclosed |