Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | TP53 | P04637 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.38 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14062581 | 0.93 | ALDH1A1 (0.50) | TDP1ALDH1A1TP53TSHRMEN1 | |
| SCHEMBL14062986 | 0.89 | TDP1 (0.44) | TDP1ALDH1A1TP53TSHRMEN1 | |
| SCHEMBL14063014 | 0.84 | TDP1 (0.50) | TDP1ALDH1A1TP53TSHRMEN1 | |
| SCHEMBL18535692 | 0.84 | TDP1 (0.70) | TDP1ALDH1A1TP53TSHRMEN1 | |
| SCHEMBL49248 | 0.84 | TDP1 (0.70) | TDP1ALDH1A1TP53TSHRMEN1 | |
| SCHEMBL21202704 | 0.84 | TDP1 (0.70) | TDP1ALDH1A1TP53TSHRMEN1 | |
| SCHEMBL14640884 | 0.84 | TDP1 (0.70) | TDP1ALDH1A1TP53TSHRMEN1 | |
| SCHEMBL2720991 | 0.84 | TDP1 (0.70) | TDP1ALDH1A1TP53TSHRMEN1 | |
| SCHEMBL11737473 | 0.83 | TDP1 (0.49) | TDP1ALDH1A1TP53TSHRMEN1 | |
| SCHEMBL14063011 | 0.83 | ALDH1A1 (0.51) | TDP1ALDH1A1TP53TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7425354-B2 | Photopolymerizable liquid crystal composition, its polymer or polymer composition, and optical compensation element | CHISSO CORPORATION (JP) | 2008-09-16 | — | — | US | disclosed |