Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14063014 | 0.90 | TDP1 (0.50) | TDP1ALDH1A1TP53TSHRHIF1A | |
| SCHEMBL14063011 | 0.89 | ALDH1A1 (0.51) | TDP1ALDH1A1TP53TSHRHIF1A | |
| SCHEMBL14063029 | 0.87 | ALDH1A1 (0.50) | TDP1ALDH1A1TP53TSHRHIF1A | |
| SCHEMBL14062810 | 0.84 | TDP1 (0.44) | TDP1ALDH1A1TP53TSHRHIF1A | |
| SCHEMBL14062994 | 0.83 | TDP1 (0.56) | TDP1ALDH1A1TP53TSHRHIF1A | |
| SCHEMBL11747205 | 0.83 | TDP1 (0.59) | TDP1ALDH1A1TP53TSHRHIF1A | |
| SCHEMBL11743286 | 0.82 | TDP1 (0.60) | TDP1ALDH1A1TP53TSHRHIF1A | |
| SCHEMBL2527003 | 0.81 | TDP1 (0.66) | TDP1ALDH1A1TP53TSHRHIF1A | |
| SCHEMBL2531000 | 0.81 | TDP1 (0.66) | TDP1ALDH1A1TP53TSHRHIF1A | |
| SCHEMBL1959536 | 0.81 | TDP1 (0.66) | TDP1ALDH1A1TP53TSHRHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4060609-A | ANTICHOLESTEROL | MERCH PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-11-29 | — | — | US | disclosed |