Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 3/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 6/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14063029 | 0.86 | ALDH1A1 (0.50) | GRM2ALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL14063038 | 0.85 | ALDH1A1 (0.42) | GRM2ALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL14063027 | 0.83 | TDP1 (0.42) | GRM2ALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL14062995 | 0.82 | GRM2 (0.39) | GRM2HTR2A | |
| SCHEMBL14063004 | 0.82 | ALDH1A1 (0.41) | GRM2ALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL14063024 | 0.81 | FFAR1 (0.36) | NR1H4FFAR4S1PR1TDP1FFAR1 | |
| SCHEMBL14063013 | 0.80 | CHKA (0.38) | GRM2CYP3A4HTR2A | |
| SCHEMBL14062918 | 0.80 | MAOB (0.40) | GRM2NR1H4FFAR4F10MAOB | |
| SCHEMBL14063011 | 0.80 | ALDH1A1 (0.51) | ALDH1A1TP53CYP3A4TSHRSMN1; SMN2 | |
| SCHEMBL14063012 | 0.77 | TDP1 (0.40) | GRM2ALDH1A1TP53CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7425354-B2 | Photopolymerizable liquid crystal composition, its polymer or polymer composition, and optical compensation element | CHISSO CORPORATION (JP) | 2008-09-16 | — | — | US | disclosed |