Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 3/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | CHKA | P35790 | 1/20 | 0.36 |
| ▸ | CALML3 | P27482 | 2/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14063013 | 0.92 | CHKA (0.38) | GRM2HTR2ACHKACALML3PDE3B | |
| SCHEMBL14062857 | 0.87 | GRM2 (0.43) | GRM2HTR2ACHKA | |
| SCHEMBL14062587 | 0.87 | CYP17A1 (0.47) | GRM2HTR2AKIF11CYP17A1CYP11B1 | |
| SCHEMBL14063166 | 0.84 | CYP3A4 (0.35) | GRM2HTR2A | |
| SCHEMBL14062992 | 0.83 | CHKA (0.35) | GRM2HTR2ACHKA | |
| SCHEMBL14063033 | 0.82 | GRM2 (0.41) | GRM2HTR2A | |
| SCHEMBL14063010 | 0.80 | MGLL (0.38) | — | |
| SCHEMBL708540 | 0.80 | MGLL (0.38) | — | |
| SCHEMBL14062723 | 0.79 | MAOB (0.42) | GRM2 | |
| SCHEMBL14062596 | 0.79 | CYP11B1 (0.48) | CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7425354-B2 | Photopolymerizable liquid crystal composition, its polymer or polymer composition, and optical compensation element | CHISSO CORPORATION (JP) | 2008-09-16 | — | — | US | disclosed |