SCHEMBL14063388

SCHEMBL14063388

CC(=O)OCc1ccc(N(c2ccccc2)c2ccc(COC(C)=O)cc2)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 0.70
HPGD P15428 3/20 0.50
MAPT P10636 2/20 0.50
MAPK1 P28482 3/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
KMT2A Q03164 2/20 0.44
SLC6A2 P23975 1/20 0.44
SLC6A3 Q01959 1/20 0.44
CYP3A4 P08684 2/20 0.44
IDH1 O75874 1/20 0.43
TSHR P16473 4/20 0.42
KDM4E B2RXH2 2/20 0.42
NPC1 O15118 1/20 0.42
GAA P10253 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
HSD17B10 Q99714 1/20 0.42
GLA P06280 1/20 0.42
LMNA P02545 1/20 0.41
HCAR2 Q8TDS4 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL159711 1.00 ALDH1A1 (0.70) ALDH1A1HPGDMAPTMAPK1L3MBTL1
SCHEMBL14063390 0.93 ALDH1A1 (0.62) ALDH1A1HPGDMAPTMAPK1L3MBTL1
SCHEMBL14063393 0.92 ALDH1A1 (0.64) ALDH1A1HPGDMAPTTSHRNPC1
SCHEMBL14063398 0.92 ALDH1A1 (0.64) ALDH1A1HPGDMAPTTSHRNPC1
SCHEMBL9581057 0.92 ALDH1A1 (0.64) ALDH1A1HPGDMAPTTSHRNPC1
SCHEMBL4764759 0.90 ALDH1A1 (0.57) ALDH1A1HPGDMAPTKMT2ACYP3A4
SCHEMBL14063414 0.88 ALDH1A1 (0.56) ALDH1A1HPGDMAPTMAPK1KMT2A
SCHEMBL14063394 0.86 ALDH1A1 (0.55) ALDH1A1HPGDMAPTMAPK1CYP3A4
SCHEMBL14063396 0.85 ALDH1A1 (0.51) ALDH1A1HPGDMAPTTDP1KMT2A
SCHEMBL12751465 0.85 ALDH1A1 (0.51) ALDH1A1HPGDMAPTMAPK1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8475982-B2 Charge-transporting compound, electrophotographic photoreceptor, image-forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2013-07-02 US disclosed
US-8475982-B2 Charge-transporting compound, electrophotographic photoreceptor, image-forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2013-07-02 US disclosed
US-8426093-B2 photosensitive layer has a charge transferring compound having hole transportation ability; hardening by heating, stable electrical properties FUJI XEROX CO., LTD. (JP) 2013-04-23 US disclosed
US-8426093-B2 photosensitive layer has a charge transferring compound having hole transportation ability; hardening by heating, stable electrical properties FUJI XEROX CO., LTD. (JP) 2013-04-23 US disclosed
US-20080220356-A1 Electrophotographic photoreceptor, process cartridge and image-forming apparatus FUJI XEROX CO., LTD. (JP) 2008-09-11 US disclosed
US-20080220356-A1 Electrophotographic photoreceptor, process cartridge and image-forming apparatus FUJI XEROX CO., LTD. (JP) 2008-09-11 US disclosed