SCHEMBL9581057

SCHEMBL9581057

CC(=O)OCc1ccc(-c2ccc(N(c3ccc(-c4ccccc4)cc3)c3ccc(-c4ccc(COC(C)=O)cc4)cc3)cc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.64
RAB9A P51151 2/20 0.48
NPC1 O15118 1/20 0.48
MAPT P10636 2/20 0.47
HPGD P15428 1/20 0.47
NAAA Q02083 3/20 0.45
EPHX1 P07099 1/20 0.45
GSTA2 P09210 1/20 0.44
GSTM1 P09488 1/20 0.44
ENPP2 Q13822 1/20 0.43
ABCC4 O15439 1/20 0.43
LMNA P02545 1/20 0.43
GAA P10253 1/20 0.43
TSHR P16473 1/20 0.43
PTGS1 P23219 1/20 0.43
HTT P42858 1/20 0.43
IDO1 P14902 1/20 0.43
AGXT P21549 1/20 0.43
MMP12 P39900 1/20 0.43
GPR84 Q9NQS5 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14063393 1.00 ALDH1A1 (0.64) ALDH1A1RAB9ANPC1MAPTHPGD
SCHEMBL14063398 1.00 ALDH1A1 (0.64) ALDH1A1RAB9ANPC1MAPTHPGD
SCHEMBL14063414 0.94 ALDH1A1 (0.56) ALDH1A1RAB9ANPC1MAPTHPGD
SCHEMBL14063388 0.92 ALDH1A1 (0.70) ALDH1A1NPC1MAPTHPGDLMNA
SCHEMBL159711 0.92 ALDH1A1 (0.70) ALDH1A1NPC1MAPTHPGDLMNA
SCHEMBL487227 0.90 ALDH1A1 (0.78) ALDH1A1RAB9ANPC1MAPTNAAA
SCHEMBL14063413 0.89 ALDH1A1 (0.51) ALDH1A1RAB9ANPC1MAPTHPGD
SCHEMBL14063417 0.89 ALDH1A1 (0.51) ALDH1A1RAB9ANPC1MAPTHPGD
SCHEMBL14063390 0.88 ALDH1A1 (0.62) ALDH1A1NPC1MAPTHPGDLMNA
SCHEMBL14063397 0.88 ALDH1A1 (0.50) ALDH1A1RAB9ANPC1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4869988-A Photoconductive imaging members with N,N-bis(biarylyl)aniline, or tris(biarylyl)amine charge transporting components XEROX CORPORATION (US) 1989-09-26 US claimed
US-5227449-A Polydiphenylsiloxane-Carbonate Block Polymers XEROX CORPORATION (US) 1993-07-13 US disclosed
US-5215844-A Photoconductive imaging members with polyhydroxy ether binders XEROX CORPORATION (US) 1993-06-01 US disclosed
US-5166021-A Multilayer imaging member with charge generating and charge transport layers XEROX CORPORATION (US) 1992-11-24 US disclosed
US-5162485-A Binders in charge transport or charge generation layers XEROX CORPORATION (US) 1992-11-10 US disclosed
US-5080987-A Photoconductive imaging members with polycarbonate binders XEROX CORPORATION (US) 1992-01-14 US disclosed
US-5011906-A Photoconductive imaging members with N,N-bis(biarylyl)aniline charge transport polymers XEROX CORPORATION (US) 1991-04-30 US disclosed
US-5008169-A Photoconductive imaging members with polyphosphazenes XEROX CORPORATION (US) 1991-04-16 US disclosed
US-5004663-A Photoconductive imaging members with polyphosphazene binders XEROX CORPORATION (US) 1991-04-02 US disclosed
US-4959288-A Photoconductive imaging members with diaryl biarylylamine copolymer charge transport layers XEROX CORPORATION (US) 1990-09-25 US disclosed
US-4946754-A Photoconductive imaging members with diaryl biarylylamine charge transporting components XEROX CORPORATION (US) 1990-08-07 US disclosed
US-4937165-A Photoconductive imaging members with N,N-bis(biarylyl)aniline charge transport polymers XEROX CORPORATION (US) 1990-06-26 US disclosed
US-4869988-A Photoconductive imaging members with N,N-bis(biarylyl)aniline, or tris(biarylyl)amine charge transporting components XEROX CORPORATION (US) 1989-09-26 US disclosed
US-4869988-A Photoconductive imaging members with N,N-bis(biarylyl)aniline, or tris(biarylyl)amine charge transporting components XEROX CORPORATION (US) 1989-09-26 US disclosed