Mannitol

Mannitol

SCHEMBL1406343

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nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 1.00
L3MBTL1 Q9Y468 1/20 1.00
TDP1 Q9NUW8 2/20 0.92
KDM4E B2RXH2 2/20 0.58
PDE4A P27815 1/20 0.58
USP2 O75604 1/20 0.52
SLCO1B1 Q9Y6L6 1/20 0.52
ALDH1A1 P00352 2/20 0.44
MAPT P10636 1/20 0.39
TOP1 P11387 1/20 0.38
MGAM O43451 2/20 0.35
SI P14410 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Mannitol SCHEMBL2477078 1.00 LMNA (1.00) LMNAL3MBTL1TDP1KDM4EPDE4A
Mannitol SCHEMBL2297640 1.00 LMNA (1.00) LMNAL3MBTL1TDP1KDM4EPDE4A
Sorbitol SCHEMBL763 1.00 LMNA (1.00) LMNAL3MBTL1TDP1KDM4EPDE4A
Mannitol SCHEMBL20594083 1.00 LMNA (1.00) LMNAL3MBTL1TDP1KDM4EPDE4A
Mannitol SCHEMBL20594082 1.00 LMNA (1.00) LMNAL3MBTL1TDP1KDM4EPDE4A
Mannitol SCHEMBL23066399 1.00 LMNA (1.00) LMNAL3MBTL1TDP1KDM4EPDE4A
Mannitol SCHEMBL13187369 1.00 LMNA (1.00) LMNAL3MBTL1TDP1KDM4EPDE4A
Mannitol SCHEMBL21837180 1.00 LMNA (1.00) LMNAL3MBTL1TDP1KDM4EPDE4A
Mannitol SCHEMBL20567656 1.00 LMNA (1.00) LMNAL3MBTL1TDP1KDM4EPDE4A
Mannitol SCHEMBL12455929 1.00 LMNA (1.00) LMNAL3MBTL1TDP1KDM4EPDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116083450-A Mannitol anabolism combined gene and combined enzyme 中国海洋大学 2023-05-09 CN claimed
EP-3272345-B1 SOLID PREPARATION CONTAINING ANTIOXIDANT AGENT DAIICHI SANKYO CO LTD (JP) 2019-10-16 EP claimed
EP-3078667-B1 FORMULATION OF BORONIC ACID COMPOUNDS THE UNITED STATES OF AMERICA REPRESENTED BY THE SEC DEP OF HEALTH AND HUMAN SERVICES (US) 2018-11-21 EP claimed
EP-1355910-B1 FORMULATION OF BORONIC ACID COMPOUNDS US OF AMERICA REPRESENTED BY THE SECRETARY DEPT OF HEALTH AND HUMAN SERVICES (US) 2011-03-09 EP claimed
EP-1229917-B1 PHARMACEUTICAL COMPOSITIONS AND PREPARATIONS FOR TREATMENT OF METABOLIC BONE DISEASE YUYU PHARMA INC (KR) 2008-12-17 EP claimed
CN-118256519-A Application of disease-resistant related protein TaMYB22 in regulation and control of plant stripe rust resistance 西北农林科技大学深圳研究院 2024-06-28 CN disclosed
CN-114950391-B Modified silica gel stationary phase, hydrophilic chromatographic column, and preparation method and application thereof 襄阳市中心医院 2024-06-25 CN disclosed
WO-2024040356-A1 MUCOADHESIVE PHARMACEUTICAL DOSAGE FORM FOR UNIDIRECTIONAL RELEASE OF PEPTIDE THERAPEUTIC PARTICLES THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2024-02-29 WO disclosed
CN-111500619-B Application of BXL gene or encoded protein thereof 中国科学院分子植物科学卓越创新中心 2023-06-23 CN disclosed
CN-116083450-A Mannitol anabolism combined gene and combined enzyme 中国海洋大学 2023-05-09 CN disclosed
CN-114088855-B Feces biomarker for early diagnosis of tibial cartilage dysplasia of broiler chicken and application thereof 河南农业大学 2022-10-28 CN disclosed
CN-110129322-B Bna-miR393 application in regulation and control of brassica napus reproductive organ development process 扬州大学 2022-08-26 CN disclosed
EP-1401532-A1 METHOD FOR NON-INVASIVELY DETERMINING THE RELATIVE LEVELS OF TWO BIOLOGICAL SUBSTANCES UNIVERSITE DE GENEVE (CH) 2004-03-31 EP disclosed
WO-2003019198-A2 METHODS RELATING TO TREATMENT OF ATHEROSCLEROSIS CAMBRIDGE THERANOSTICS LTD (GB) 2003-03-06 WO disclosed
WO-2003000340-A1 METHOD FOR NON-INVASIVELY DETERMINING THE RELATIVE LEVELS OF TWO BIOLOGICAL SUBSTANCES UNIVERSITE DE GENEVE (CH) 2003-01-03 WO disclosed
EP-0920529-A1 METHOD OF AND GROWTH MEDIUM FOR DETECTING MICRO-ORGANISMS IN A SAMPLE The University of Lincolnshire & Humberside (GB) 1999-06-09 EP disclosed
WO-1998007882-A1 METHOD OF AND GROWTH MEDIUM FOR DETECTING MICRO-ORGANISMS IN A SAMPLE THE UNIVERSITY OF LINCOLNSHIRE & HUMBERSIDE (GB) 1998-02-26 WO disclosed
US-5573777-A Pulverulent mannitol of moderate friability and process for its preparation ROQUETTE FRERES (FR) 1996-11-12 US disclosed
US-4661647-A FREE FROM BINDER ROQUETTE FRERES (FR) 1987-04-28 US disclosed
US-4460683-A IMMOBILIZED ENZYMES, POLYSACCHARIDES, POLYUINYL PYRROLIDONE BOEHRINGER MANNHEIM GMBH (DE) 1984-07-17 US disclosed