Sorbitol

Sorbitol

SCHEMBL763

OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CO

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 1.00
L3MBTL1 Q9Y468 1/20 1.00
TDP1 Q9NUW8 2/20 0.92
KDM4E B2RXH2 2/20 0.58
PDE4A P27815 1/20 0.58
USP2 O75604 1/20 0.52
SLCO1B1 Q9Y6L6 1/20 0.52
ALDH1A1 P00352 2/20 0.44
MAPT P10636 1/20 0.39
TOP1 P11387 1/20 0.38
MGAM O43451 2/20 0.35
SI P14410 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Mannitol SCHEMBL1406343 1.00 LMNA (1.00) LMNAL3MBTL1TDP1KDM4EPDE4A
Mannitol SCHEMBL2477078 1.00 LMNA (1.00) LMNAL3MBTL1TDP1KDM4EPDE4A
Mannitol SCHEMBL2297640 1.00 LMNA (1.00) LMNAL3MBTL1TDP1KDM4EPDE4A
Mannitol SCHEMBL20594083 1.00 LMNA (1.00) LMNAL3MBTL1TDP1KDM4EPDE4A
Mannitol SCHEMBL20594082 1.00 LMNA (1.00) LMNAL3MBTL1TDP1KDM4EPDE4A
Mannitol SCHEMBL23066399 1.00 LMNA (1.00) LMNAL3MBTL1TDP1KDM4EPDE4A
Mannitol SCHEMBL13187369 1.00 LMNA (1.00) LMNAL3MBTL1TDP1KDM4EPDE4A
Mannitol SCHEMBL21837180 1.00 LMNA (1.00) LMNAL3MBTL1TDP1KDM4EPDE4A
Mannitol SCHEMBL20567656 1.00 LMNA (1.00) LMNAL3MBTL1TDP1KDM4EPDE4A
Mannitol SCHEMBL12455929 1.00 LMNA (1.00) LMNAL3MBTL1TDP1KDM4EPDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 1128601 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6372755-B1 None US claimed
US-9974730-B2 Oral care compositions and methods COLGATE-PALMOLIVE COMPANY (US) 2018-05-22 US claimed
US-9975979-B2 Method of preparing superabsorbent polymer LG CHEM, LTD. (KR) 2018-05-22 US claimed
US-9974723-B2 Oral care compositions comprising calcium carbonate and silica COLGATE-PALMOLIVE COMPANY (US) 2018-05-22 US claimed
US-9974735-B2 Depilatory compositions RECKITT & COLMAN (OVERSEAS) LIMITED (GB) 2018-05-22 US claimed
US-9976168-B2 Substance measurement method and measurement device employing electrochemical biosensor ARKRAY, INC. (JP) 2018-05-22 US claimed
WO-2018087782-A1 SYNERGISTIC DIETARY SUPPLEMENT COMPOSITIONS FOR IMPROVING BRAIN HEALTH LAILA NUTRACEUTICALS (IN) 2018-05-17 WO claimed
WO-2018087501-A1 POLYMER COMPOSITION THAT CAN BE EXTRUDED INTO AN OBJECT THAT IS PERMEABLE TO WATER VAPOUR ARKEMA FRANCE (FR) 2018-05-17 WO claimed
US-20180133215-A1 SOMCL-9112 SOLID DISPERSION AND PREPARATION METHOD THEREOF AND SOMCL-9112 SOLID PREPARATION CONTAINING SOMCL-9112 SOLID DISPERSION SHANGHAI ACEBRIGHT PHARMACEUTICALS CO., LTD. (CN) 2018-05-17 US claimed
WO-2018085918-A1 NOVEL METHODS FOR CREATION OF SUB-MICRON BIOCARBON MATERIALS FROM BIOMASS AND THEIR FIELDS OF APPLICATION UNIVERSITY OF GUELPH (CA) 2018-05-17 WO claimed
US-3959511-A Method of making a dry fibrous meat-like pet food and composition thereof THE QUAKER OATS COMPANY (US) 1976-05-25 US claimed
US-3957922-A USED FOR POLYURETHANES BASF WYANDOTTE CORPORATION (US) 1976-05-18 US claimed
US-3957964-A Dentifrice containing encapsulated flavoring COLGATE-PALMOLIVE COMPANY (US) 1976-05-18 US claimed
US-3952112-A Methods for treating dried fruits to improve softness retention characteristics KELLOGG COMPANY (US) 1976-04-20 US claimed
US-3951945-A Method for the preparation of esters of polyalcohols B.V. CHEMIE COMBINATIE AMSTERDAM C.C.A. (NL) 1976-04-20 US claimed
US-3950258-A SALT OF SULFURIC ESTER OF POLYOXYALKYLENE COMPOUND SANYO CHEMICAL INDUSTRIES, LTD. (JA) 1976-04-13 US claimed
US-3948833-A Compositions for rigid asbestos - reinforced polyvinyl chloride CENTRE FOR INDUSTRIAL RESEARCH (CIR) LTD. (IL) 1976-04-06 US claimed
US-3943171-A Method of producing acrylamide with a Raney copper catalyst NALCO CHEMICAL COMPANY (US) 1976-03-09 US claimed
US-3935325-A VEGETABLE FAT AND PROTEIN, STEAROYL-2-LACTYLIC ACID, MONOGLYCERIDE, PARTIAL FATTY ACID ESTERS OF MANNITOL OR SORBITOL SCM CORPORATION (US) 1976-01-27 US claimed
US-3935173-A POLYESTER TYPE OLIGO(METH) ACRYLATE TOAGOSEI CHEMICAL INDUSTRIAL CO. LTD. (JA) 1976-01-27 US claimed