Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 18/20 | 0.81 |
| ▸ | CYP2D6 | P10635 | 9/20 | 0.81 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.81 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.63 |
| ▸ | GSK3A | P49840 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4024980 | 0.89 | GSK3B (1.00) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL14063548 | 0.89 | GSK3B (1.00) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL4025571 | 0.89 | GSK3B (1.00) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL2116045 | 0.84 | GSK3B (0.89) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL2116047 | 0.84 | GSK3B (0.89) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL2116909 | 0.84 | GSK3B (0.89) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL3805877 | 0.84 | GSK3B (0.58) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| Hydrochloric Acid SCHEMBL2119087 | 0.83 | GSK3B (0.87) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL14063524 | 0.83 | GSK3B (0.65) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL13910887 | 0.82 | GSK3B (0.86) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7427615-B2 | 3-substituted-4-pyrimidone derivatives | MITSUBISHI PHARMA CORPORATION (JP) | 2008-09-23 | — | — | US | disclosed |
| US-7427615-B2 | 3-substituted-4-pyrimidone derivatives | MITSUBISHI PHARMA CORPORATION (JP) | 2008-09-23 | — | — | US | disclosed |