Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 19/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 8/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.58 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.46 |
| ▸ | GSK3A | P49840 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL497069 | 0.91 | GSK3B (0.70) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL497313 | 0.91 | GSK3B (0.70) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL14063525 | 0.84 | GSK3B (0.81) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL87719 | 0.80 | GSK3B (0.75) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL87851 | 0.80 | GSK3B (0.75) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL88509 | 0.79 | GSK3B (0.76) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL14063705 | 0.79 | GSK3B (0.79) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL8340473 | 0.76 | GSK3B (0.49) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL13910887 | 0.76 | GSK3B (0.86) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL13910604 | 0.76 | GSK3B (0.90) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2266979-A1 | 2-morpholino-4-pyrimidone compounds | Mitsubishi Tanabe Pharma Corporation (JP) | 2010-12-29 | — | — | EP | disclosed |