Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 4/20 | 0.53 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.51 |
| ▸ | ALB | P02768 | 2/20 | 0.49 |
| ▸ | GNPAT | O15228 | 1/20 | 0.49 |
| ▸ | GLP1R | P43220 | 8/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | FNTA | P49354 | 2/20 | 0.44 |
| ▸ | FNTB | P49356 | 2/20 | 0.44 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14118084 | 0.89 | FOLH1 (0.46) | NOD1FOLH1ALBGLP1R | |
| SCHEMBL13057101 | 0.88 | FOLH1 (0.55) | NOD1FOLH1ALBGNPATGLP1R | |
| SCHEMBL13674388 | 0.87 | GNPAT (0.64) | NOD1FOLH1ALBGNPATGLP1R | |
| SCHEMBL23452088 | 0.86 | NOD1 (0.61) | NOD1FOLH1ALBGLP1REPHX2 | |
| SCHEMBL13057100 | 0.86 | NOD1 (0.61) | NOD1FOLH1ALBGLP1REPHX2 | |
| SCHEMBL29617648 | 0.85 | NOD1 (0.51) | NOD1FOLH1ALBGNPATGLP1R | |
| SCHEMBL13223744 | 0.84 | ALB (0.46) | NOD1FOLH1ALBGLP1REPHX2 | |
| SCHEMBL32679724 | 0.84 | NOD1 (0.60) | NOD1FOLH1ALBGLP1REPHX2 | |
| SCHEMBL13057104 | 0.84 | NOD1 (0.67) | NOD1FOLH1ALBGLP1REPHX2 | |
| SCHEMBL21986240 | 0.84 | NOD1 (0.74) | NOD1GLP1REPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8546493-B2 | Multi-armed, monofunctional, and hydrolytically stable derivatives of poly(ethylene glycol) and related polymers for modification of surfaces and molecules | NEKTAR THERAPEUTICS (US) | 2013-10-01 | — | — | US | disclosed |
| US-20130177961-A1 | MULTI-ARMED, MONOFUNCTIONAL, AND HYDROLYTICALLY STABLE DERIVATIVES OF POLY(ETHYLENE GLYCOL) AND RELATED POLYMERS FOR MODIFICATION OF SURFACES AND MOLECULES | NEKTAR THERAPEUTICS (US) | 2013-07-11 | — | — | US | disclosed |
| US-7419600-B2 | Method for purifying a branched water-soluble polymer | NEKTAR THERAPEUTICS AL, CORPORATION (US) | 2008-09-02 | — | — | US | disclosed |