Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL142918 | 0.92 | ADRB2 (0.43) | ADRB2GSK3BKDM4EPOLBALDH1A1 | |
| SCHEMBL13625737 | 0.91 | ADRB2 (0.44) | ADRB2GSK3BKDM4EPOLBALDH1A1 | |
| SCHEMBL116196 | 0.84 | ADRB2 (0.48) | ADRB2KDM4EPOLBALDH1A1TDP1 | |
| SCHEMBL12836881 | 0.84 | ADRB2 (0.44) | ADRB2GSK3BKDM4EPOLBALDH1A1 | |
| SCHEMBL140693 | 0.82 | ADRB2 (0.44) | ADRB2GSK3BKDM4EPOLBALDH1A1 | |
| SCHEMBL140639 | 0.82 | DPP4 (0.34) | GSK3BKDM4EPOLBALDH1A1LMNA | |
| SCHEMBL116248 | 0.79 | ADRB2 (0.49) | ADRB2KDM4EPOLBALDH1A1TDP1 | |
| SCHEMBL142688 | 0.79 | ADRB2 (0.41) | ADRB2KDM4EPOLBALDH1A1LMNA | |
| SCHEMBL12836900 | 0.78 | KDM4E (0.43) | GSK3BKDM4EPOLBALDH1A1LMNA | |
| SCHEMBL114597 | 0.76 | ADRB2 (0.49) | ADRB2KDM4EPOLBALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120058989-A1 | ANTIBACTERIAL FLUOROQUINOLONE ANALOGS | ACHAOGEN, INC. (US) | 2012-03-08 | — | — | US | disclosed |
| WO-2009137130-A2 | ANTIBACTERIAL FLUOROQUINOLONE ANALOGS | ACHAOGEN, INC. (US) | 2009-11-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120058989-A1 | ANTIBACTERIAL FLUOROQUINOLONE ANALOGS | RECQL, BLVRB, NQO2 | ADRB2 702/4885GSK3B 3846/4885KDM4E 2563/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.