Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 5/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 5/20 | 0.46 |
| ▸ | PREP | P48147 | 1/20 | 0.40 |
| ▸ | FAP | Q12884 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.40 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22600820 | 0.82 | NPC1 (0.44) | CHRNB4CHRNA3ACEKMT2A | |
| SCHEMBL18473157 | 0.82 | CHRNB4 (0.43) | CHRNB4CHRNA3HTT | |
| SCHEMBL9892968 | 0.82 | CHRNB4 (0.43) | CHRNB4CHRNA3HTT | |
| SCHEMBL26765974 | 0.82 | NPC1 (0.44) | CHRNB4CHRNA3ACEKMT2A | |
| SCHEMBL2734906 | 0.82 | CHRNB4 (0.43) | CHRNB4CHRNA3HTT | |
| SCHEMBL24736540 | 0.82 | CHRNB4 (0.43) | CHRNB4CHRNA3HTT | |
| SCHEMBL22810961 | 0.80 | POLB (0.49) | ACEALDH1A1KMT2A | |
| SCHEMBL21699252 | 0.80 | POLB (0.49) | ACEALDH1A1KMT2A | |
| SCHEMBL9892967 | 0.80 | POLB (0.49) | ACEALDH1A1KMT2A | |
| SCHEMBL2734908 | 0.80 | POLB (0.49) | ACEALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7423116-B2 | Pentapeptide compounds and uses related thereto | SEATTLE GENETICS INC. (US) | 2008-09-09 | — | — | US | disclosed |
| US-7423116-B2 | Pentapeptide compounds and uses related thereto | SEATTLE GENETICS INC. (US) | 2008-09-09 | — | — | US | disclosed |