SCHEMBL22600820 — predicted protein targets

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	NPC1	O15118	2/20	0.44

▸	RAB9A	P51151	2/20	0.44

▸	CHRNB4	P30926	2/20	0.43

▸	CHRNA3	P32297	2/20	0.43

▸	LMNA	P02545	2/20	0.43

▸	GAA	P10253	1/20	0.42

▸	MEN1	O00255	1/20	0.41

▸	KMT2A	Q03164	1/20	0.41

▸	SLC2A1	P11166	1/20	0.40

▸	MME	P08473	1/20	0.40

▸	ACE	P12821	1/20	0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL26765974	1.00	NPC1 (0.44)	NPC1RAB9ACHRNB4CHRNA3LMNA
SCHEMBL22810961	0.90	POLB (0.49)	LMNAGAAKMT2AMMEACE
SCHEMBL2734908	0.90	POLB (0.49)	LMNAGAAKMT2AMMEACE
SCHEMBL15313443	0.90	POLB (0.49)	LMNAGAAKMT2AMMEACE
SCHEMBL21699252	0.90	POLB (0.49)	LMNAGAAKMT2AMMEACE
SCHEMBL9892967	0.90	POLB (0.49)	LMNAGAAKMT2AMMEACE
SCHEMBL19647312	0.89	GAA (0.54)	LMNAGAA
SCHEMBL18912329	0.89	GAA (0.54)	LMNAGAA
SCHEMBL18683750	0.87	NPC1 (0.41)	NPC1RAB9ALMNAGAAMEN1
SCHEMBL22476513	0.85	GAA (0.42)	GAAACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2020219770-A1	ANTI-CD117 ANTIBODIES AND USES THEREOF	Magenta Therapeutics, Inc. (US)	2020-10-29	—	—	WO	disclosed