Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | ACE | P12821 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MME | P08473 | 8/20 | 0.46 |
| ▸ | CPA1 | P15085 | 5/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22810961 | 1.00 | POLB (0.49) | POLBACEALDH1A1HSD17B10MME | |
| SCHEMBL9892967 | 1.00 | POLB (0.49) | POLBACEALDH1A1HSD17B10MME | |
| SCHEMBL2734908 | 1.00 | POLB (0.49) | POLBACEALDH1A1HSD17B10MME | |
| SCHEMBL15313443 | 1.00 | POLB (0.49) | POLBACEALDH1A1HSD17B10MME | |
| SCHEMBL18912329 | 0.93 | GAA (0.54) | POLBALDH1A1HSD17B10GAALMNA | |
| SCHEMBL19647312 | 0.93 | GAA (0.54) | POLBALDH1A1HSD17B10GAALMNA | |
| SCHEMBL22600820 | 0.90 | NPC1 (0.44) | ACEMMEGAALMNAKMT2A | |
| SCHEMBL26765974 | 0.90 | NPC1 (0.44) | ACEMMEGAALMNAKMT2A | |
| SCHEMBL22476513 | 0.89 | GAA (0.42) | ACEALDH1A1HSD17B10GAA | |
| SCHEMBL2755704 | 0.89 | ALDH1A1 (0.52) | POLBACEALDH1A1HSD17B10MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3607996-B1 | ANTIBODY-DRUG-CONJUGATE AND ITS USE FOR THE TREATMENT OF CANCER | PF MEDICAMENT (FR) | 2023-01-04 | — | — | EP | disclosed |
| EP-3607996-A1 | ANTIBODY-DRUG-CONJUGATE AND ITS USE FOR THE TREATMENT OF CANCER | PIERRE FABRE MEDICAMENT (FR) | 2020-02-12 | — | — | EP | disclosed |