Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RARA | P10276 | 1/20 | 0.38 |
| ▸ | RARB | P10826 | 1/20 | 0.38 |
| ▸ | RARG | P13631 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14064298 | 0.90 | APEX1 (0.40) | HRH3APEX1ALDH1A1KMT2ARAB9A | |
| SCHEMBL14064293 | 0.86 | NPC1 (0.42) | ALDH1A1KMT2ARAB9ASMN1; SMN2KDM4E | |
| SCHEMBL14579498 | 0.83 | HRH3 (0.45) | HRH3APEX1ALDH1A1KMT2ARAB9A | |
| SCHEMBL14064295 | 0.82 | APEX1 (0.46) | HRH3APEX1ALDH1A1KMT2ARAB9A | |
| SCHEMBL14064291 | 0.77 | NPC1 (0.40) | ALDH1A1KMT2ARAB9ASMN1; SMN2KDM4E | |
| SCHEMBL14064284 | 0.76 | HRH3 (0.40) | HRH3GAARARARARBRARG | |
| SCHEMBL14071901 | 0.75 | HRH3 (0.39) | HRH3ALDH1A1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL3064482 | 0.74 | APEX1 (0.43) | HRH3APEX1ALDH1A1KMT2ARAB9A | |
| SCHEMBL16153980 | 0.74 | TDP2 (0.49) | ALDH1A1KMT2ARAB9ASMN1; SMN2KDM4E | |
| SCHEMBL14064282 | 0.73 | PTGDR2 (0.47) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7420062-B2 | Hetaryl-substituted pyrazolidindione derivatives with pesticidal characteristics | BAYER CROPSCIENCE, AG (DE) | 2008-09-02 | — | — | US | disclosed |
| US-7420062-B2 | Hetaryl-substituted pyrazolidindione derivatives with pesticidal characteristics | BAYER CROPSCIENCE, AG (DE) | 2008-09-02 | — | — | US | disclosed |
| US-20070066488-A1 | Hetaryl-substituted pyrazolidindione derivatives with pesticidal characteristics | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-03-22 | — | — | US | disclosed |
| US-20070066488-A1 | Hetaryl-substituted pyrazolidindione derivatives with pesticidal characteristics | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070066488-A1 | Hetaryl-substituted pyrazolidindione derivatives with pesticidal characteristics | DDT, CYP1A2, HPD | HRH3 511/4885APEX1 2254/4885ALDH1A1 769/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.