SCHEMBL140644

SCHEMBL140644

COC(=O)c1ccc(B(O)O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.59
CA2 P00918 4/20 0.59
CA12 O43570 2/20 0.59
CA7 P43166 2/20 0.59
CA9 Q16790 2/20 0.59
CA14 Q9ULX7 2/20 0.59
TDP1 Q9NUW8 1/20 0.59
TSHR P16473 1/20 0.56
MAPT P10636 4/20 0.53
ALDH1A1 P00352 2/20 0.53
LOXL2 Q9Y4K0 1/20 0.52
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
ENPP2 Q13822 1/20 0.50
L3MBTL1 Q9Y468 2/20 0.48
CASP3 P42574 1/20 0.48
RAB9A P51151 1/20 0.48
SENP8 Q96LD8 1/20 0.48
SENP7 Q9BQF6 1/20 0.48
SENP6 Q9GZR1 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2040977 0.98 CA1 (0.57) CA1CA2CA12CA7CA9
SCHEMBL6605832 0.94 CA1 (0.54) CA1CA2CA12CA7CA9
SCHEMBL257872 0.91 CA1 (0.58) CA1CA2CA12CA7CA9
SCHEMBL23493574 0.89 RAB9A (0.67) CA1CA2CA12CA7CA9
SCHEMBL23493572 0.89 RAB9A (0.67) CA1CA2CA12CA7CA9
SCHEMBL28095252 0.88 CA1 (0.55) CA1CA2CA12CA7CA9
SCHEMBL18713906 0.85 CA1 (0.57) CA1CA2CA12CA7CA9
Phenylboronic Acid SCHEMBL29109684 0.84 EGFR (0.59) CA1CA2CA12CA9CA14
SCHEMBL28993944 0.83 CA1 (0.80) CA1CA2CA12CA7CA9
SCHEMBL23600 0.83 CA1 (0.80) CA1CA2CA12CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3781 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122036736-A Pyrrolo [2,3-d ] pyrimidine derivative, synthetic method and application 云南大学 2026-05-15 CN claimed
US-20250194617-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2025-06-19 US claimed
US-20250177537-A1 AN ANTIBIOTIC, METHOD OF PREPARATION AND METHOD OF TREATMENT THEREOF NATIONAL TAIWAN UNIVERSITY (TW) 2025-06-05 US claimed
US-20250169514-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2025-05-29 US claimed
CN-120040779-A Azacyclo-carbene silver catalyst based on MOF framework and preparation method and application thereof 华南理工大学 2025-05-27 CN claimed
CN-120004758-A Screening and verifying method of targeting sclerostin specific structural domain small molecule inhibitor 中山大学 2025-05-16 CN claimed
CN-117534681-B Preparation and application of aromatic ester electrochromic material with spirodipropyl dioxythiophene as core 南京林业大学 2025-05-02 CN claimed
CN-119707674-A Halogenated tetrastyryl derivative fluorescent probe and synthetic method and application thereof 海南大学 2025-03-28 CN claimed
CN-119677765-A Method for producing antibiotic macrocyclic peptides 豪夫迈·罗氏有限公司 2025-03-21 CN claimed
CN-115959993-B Synthesis method of 2-aryl propionic acid compound 山东中医药大学 2025-01-07 CN claimed
EP-0973704-B1 PROCESS FOR THE MANUFACTURE OF ARYLSULFONYL CHLORIDE ASTRAZENECA AB (SE) 2004-10-06 EP claimed
US-20040167257-A1 PREPARATION OF METAL NANOPARTICLES AND NANOCOMPOSITES THEREFROM APS LABORATORY 2004-08-26 US claimed
US-20040159824-A1 METAL OXIDE SOLS AS NANOSCALE ADDITIVES FOR POLYMERS APS LABORATORY 2004-08-19 US claimed
WO-2004063288-A1 METAL OXIDE SOLS AS NANOSCALE ADDITIVES FOR POLYMERS APS LABORATORY (US) 2004-07-29 WO claimed
US-20030162973-A1 Process for the manufacture of arylsulfonyl chloride ASTRAZENECA UK LIMITED (GB) 2003-08-28 US claimed
EP-1093367-A4 PROTEASE INHIBITORS SMITHKLINE BEECHAM CORP (US) 2003-03-05 EP claimed
EP-1093367-A1 PROTEASE INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 2001-04-25 EP claimed
EP-0973704-A1 PROCESS FOR THE MANUFACTURE OF ARYLSULFONYL CHLORIDE ZENECA LIMITED (GB) 2000-01-26 EP claimed
WO-1999066925-A1 PROTEASE INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 1999-12-29 WO claimed
WO-1998040332-A1 PROCESS FOR THE MANUFACTURE OF ARYLSULFONYL CHLORIDE ZENECA LIMITED (GB) 1998-09-17 WO claimed