SCHEMBL28095252

SCHEMBL28095252

COC(=O)c1ccc(B(O)O)cc1.COC(=O)c1ccc(OB(O)O)cc1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.55
CA2 P00918 3/20 0.55
MAPT P10636 5/20 0.50
ENPP2 Q13822 1/20 0.48
TDP1 Q9NUW8 1/20 0.47
CA12 O43570 1/20 0.47
CA7 P43166 1/20 0.47
CA9 Q16790 1/20 0.47
CA14 Q9ULX7 1/20 0.47
STS P08842 1/20 0.46
RAB9A P51151 3/20 0.45
KMT2A Q03164 3/20 0.45
MEN1 O00255 2/20 0.45
KDM4E B2RXH2 1/20 0.45
TSHR P16473 1/20 0.44
ALDH1A1 P00352 1/20 0.43
LOXL2 Q9Y4K0 1/20 0.42
NPC1 O15118 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
ACR P10323 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1003779 0.91 CA1 (0.64) CA1CA2MAPTTDP1CA12
SCHEMBL140644 0.88 CA1 (0.59) CA1CA2MAPTENPP2TDP1
SCHEMBL31072060 0.86 CA1 (0.58) CA1CA2MAPTTDP1CA12
SCHEMBL257872 0.86 CA1 (0.58) CA1CA2MAPTENPP2TDP1
SCHEMBL31072061 0.86 CA1 (0.58) CA1CA2MAPTTDP1CA12
SCHEMBL2040977 0.86 CA1 (0.57) CA1CA2MAPTENPP2TDP1
SCHEMBL29220093 0.83 CA1 (0.55) CA1CA2MAPTTDP1CA12
SCHEMBL6605832 0.82 CA1 (0.54) CA1CA2MAPTTDP1CA12
SCHEMBL29472012 0.80 CA1 (0.55) CA1CA2MAPTTDP1CA12
SCHEMBL16351761 0.78 RAB9A (0.68) MAPTRAB9AKMT2AMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104803826-B A kind of method utilizing hexafluoropropene that aryl boric acid directly aoxidizes seven fluorine isopropylations 中国科学院上海有机化学研究所 2016-08-17 CN disclosed