SCHEMBL14064844

SCHEMBL14064844

CCCNCc1ccc(S(N)(=O)=O)cc1

nearest known ligand 0.67

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CA2 P00918 20/20 0.67
CA1 P00915 18/20 0.67
CA9 Q16790 11/20 0.67
CA12 O43570 11/20 0.67
CA4 P22748 9/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12960976 0.85 CA2 (0.66) CA2CA1CA9CA12CA4
SCHEMBL4273112 0.84 CA2 (0.47) CA2CA1CA9CA12CA4
SCHEMBL9829659 0.81 CA2 (0.60) CA2CA1CA9CA12CA4
SCHEMBL22731863 0.78 PTPRZ1 (0.47) CA2CA1CA9CA12CA4
SCHEMBL11935941 0.78 CA1 (0.77) CA2CA1CA9CA12CA4
SCHEMBL13123435 0.78 CA2 (0.66) CA2CA1CA9CA12CA4
SCHEMBL5530452 0.77 CA2 (0.66) CA2CA1CA9CA12CA4
SCHEMBL18901312 0.77 CA2 (0.66) CA2CA1CA9CA12CA4
SCHEMBL15094416 0.77 CA1 (0.75) CA2CA1CA9CA12CA4
SCHEMBL8197786 0.77 CA2 (0.70) CA2CA1CA9CA12CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1970375-A1 ARYLMETHYLENE UREA DERIVATIVE AND USE THEREOF TORAY INDUSTRIES, INC. (JP) 2008-09-17 EP disclosed