Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14064841 | 0.81 | PDE10A (0.42) | PDE10AALDH1A1ADRB2ADRB1ADRB3 | |
| SCHEMBL27352743 | 0.77 | PDE10A (0.48) | PDE10AALDH1A1ADRB2ADRB1ADRB3 | |
| SCHEMBL14064972 | 0.77 | PDE10A (0.48) | PDE10AALDH1A1ADRB2ADRB1ADRB3 | |
| SCHEMBL23865472 | 0.76 | ERCC5 (0.43) | ALDH1A1TSHRL3MBTL1CYP1A2CYP2C9 | |
| SCHEMBL3030682 | 0.73 | ALDH1A1 (0.42) | PDE10AALDH1A1ADRB2ADRB1ADRB3 | |
| SCHEMBL3030686 | 0.73 | ALDH1A1 (0.42) | PDE10AALDH1A1ADRB2ADRB1ADRB3 | |
| SCHEMBL837484 | 0.71 | ALDH1A1 (0.50) | PDE10AALDH1A1ADRB2ADRB1ADRB3 | |
| SCHEMBL7186665 | 0.69 | ALDH1A1 (0.52) | PDE10AALDH1A1ADRB2ADRB1ADRB3 | |
| Acetic Acid SCHEMBL28750958 | 0.68 | ALDH1A1 (0.57) | PDE10AALDH1A1ADRB2ADRB1ADRB3 | |
| SCHEMBL14064903 | 0.68 | PDE10A (0.42) | PDE10AALDH1A1ADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1964561-A1 | Inhibitors of IMPDH enzyme | Vertex Pharmaceuticals Incorporated (US) | 2008-09-03 | — | — | EP | disclosed |