Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC5 | P28715 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TYK2 | P29597 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16257947 | 0.79 | HPGD (0.41) | ERCC5FEN1SMN1; SMN2HPGDPOLB | |
| SCHEMBL14065183 | 0.76 | PDE10A (0.39) | SMN1; SMN2KDM4ECYP1A2CYP3A4CYP2C9 | |
| SCHEMBL11279520 | 0.75 | DEGS1 (0.41) | SMN1; SMN2HPGDKDM4ECYP3A4POLB | |
| SCHEMBL20942903 | 0.75 | SMN1; SMN2 (0.41) | ERCC5FEN1SMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL11279517 | 0.75 | DEGS1 (0.41) | SMN1; SMN2HPGDKDM4ECYP3A4POLB | |
| SCHEMBL20942904 | 0.75 | SMN1; SMN2 (0.41) | ERCC5FEN1SMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL18621223 | 0.73 | TSHR (0.43) | ERCC5FEN1SMN1; SMN2HPGDTSHR | |
| SCHEMBL9493573 | 0.73 | TSHR (0.43) | ERCC5FEN1SMN1; SMN2HPGDTSHR | |
| SCHEMBL9493577 | 0.73 | TSHR (0.43) | ERCC5FEN1SMN1; SMN2HPGDTSHR | |
| SCHEMBL16257948 | 0.71 | TSHR (0.41) | ERCC5FEN1SMN1; SMN2HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3885344-A2 | PYRIMIDINE COMPOUNDS, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USES THEREOF | InventisBio Co., Ltd. (CN) | 2021-09-29 | — | — | EP | disclosed |