Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3035550 | 0.77 | CTSK (0.33) | CTSK | |
| SCHEMBL146767 | 0.76 | — | — | |
| SCHEMBL102902 | 0.75 | — | — | |
| SCHEMBL4138238 | 0.72 | CTSK (0.47) | CTSK | |
| SCHEMBL10760394 | 0.72 | — | — | |
| SCHEMBL29655326 | 0.71 | CTSK (0.42) | CTSK | |
| SCHEMBL276891 | 0.71 | CTSK (0.42) | CTSK | |
| SCHEMBL3040229 | 0.69 | ADH1B (0.42) | CTSK | |
| SCHEMBL3034953 | 0.69 | CTSK (0.31) | CTSK | |
| SCHEMBL76606 | 0.69 | ADH1B (0.42) | CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1964561-A1 | Inhibitors of IMPDH enzyme | Vertex Pharmaceuticals Incorporated (US) | 2008-09-03 | — | — | EP | disclosed |