Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 6/20 | 0.58 |
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.58 |
| ▸ | DPP9 | Q86TI2 | 5/20 | 0.58 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.54 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.54 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.54 |
| ▸ | GSR | P00390 | 1/20 | 0.53 |
| ▸ | DPP4 | P27487 | 2/20 | 0.51 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | TLR2 | O60603 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14065666 | 1.00 | DPP7 (0.58) | DPP7DPP8DPP9GNAI3GNAO1 | |
| SCHEMBL18633064 | 1.00 | DPP7 (0.58) | DPP7DPP8DPP9GNAI3GNAO1 | |
| SCHEMBL19080499 | 0.94 | DPP7 (0.57) | DPP7DPP8DPP9GNAI3GNAO1 | |
| SCHEMBL5079730 | 0.89 | DPP8 (0.58) | DPP7DPP8DPP9GNAI3GNAO1 | |
| SCHEMBL3485077 | 0.89 | DPP7 (0.58) | DPP7DPP8DPP9GNAI3GNAO1 | |
| SCHEMBL18714213 | 0.87 | DPP7 (0.56) | DPP7DPP8DPP9GNAI3GNAO1 | |
| SCHEMBL13829054 | 0.85 | DPP7 (0.45) | DPP7DPP8DPP9GNAI3GNAO1 | |
| SCHEMBL25761063 | 0.85 | DPP7 (0.58) | DPP7DPP8DPP9GNAI3GNAO1 | |
| SCHEMBL9705058 | 0.84 | GSR (0.58) | DPP7DPP8DPP9GNAI3GNAO1 | |
| SCHEMBL2115368 | 0.84 | GSR (0.58) | DPP7DPP8DPP9GNAI3GNAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7419990-B2 | Piperidine derivatives as melanocortin-4 receptor agonists | MERCK & CO., INC. (US) | 2008-09-02 | — | — | US | disclosed |
| US-7419990-B2 | Piperidine derivatives as melanocortin-4 receptor agonists | MERCK & CO., INC. (US) | 2008-09-02 | — | — | US | disclosed |