SCHEMBL5079730

SCHEMBL5079730

CC(NC(=O)[C@@H](N)CCCCN)NC(=O)[C@@H](N)CCCCN

nearest known ligand 0.58

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
DPP8 Q6V1X1 8/20 0.58
DPP9 Q86TI2 8/20 0.58
DPP7 Q9UHL4 8/20 0.58
GNAI3 P08754 1/20 0.54
GNAO1 P09471 1/20 0.54
GNAI1 P63096 1/20 0.54
GSR P00390 1/20 0.53
DPP4 P27487 5/20 0.51
SLC15A1 P46059 1/20 0.44
MMP2 P08253 1/20 0.43
TLR2 O60603 2/20 0.42
RRM1 P23921 1/20 0.41
TERT O14746 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3485077 0.89 DPP7 (0.58) DPP8DPP9DPP7GNAI3GNAO1
SCHEMBL14065666 0.89 DPP7 (0.58) DPP8DPP9DPP7GNAI3GNAO1
SCHEMBL14065670 0.89 DPP7 (0.58) DPP8DPP9DPP7GNAI3GNAO1
SCHEMBL18633064 0.89 DPP7 (0.58) DPP8DPP9DPP7GNAI3GNAO1
SCHEMBL18714213 0.87 DPP7 (0.56) DPP8DPP9DPP7GNAI3GNAO1
SCHEMBL2115366 0.84 GSR (0.58) DPP8DPP9DPP7GNAI3GNAO1
SCHEMBL2115368 0.84 GSR (0.58) DPP8DPP9DPP7GNAI3GNAO1
SCHEMBL17510190 0.84 GSR (0.58) DPP8DPP9DPP7GNAI3GNAO1
SCHEMBL7781619 0.84 GSR (0.58) DPP8DPP9DPP7GNAI3GNAO1
SCHEMBL1641744 0.84 GSR (0.58) DPP8DPP9DPP7GNAI3GNAO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3431140-B1 NERVE REGENERATION-INDUCING MATERIAL TAZUKE KOFUKAI (JP) 2024-03-27 EP claimed
US-20210283304-A1 NERVE REGENERATION-INDUCING MATERIAL TAZUKE KOFUKAI (JP) 2021-09-16 US claimed
US-11052174-B2 Nerve regeneration-inducing material Kofukai, Tazuke (JP) 2021-07-06 US claimed
US-20200268931-A1 BRAIN DAMAGE RECOVERY MATERIAL TAZUKE KOFUKAI (JP) 2020-08-27 US claimed
US-20190083678-A1 NERVE REGENERATION-INDUCING MATERIAL TAZUKE KOFUKAI (JP) 2019-03-21 US claimed
EP-3431140-A1 NERVE REGENERATION-INDUCING MATERIAL Tazuke Kofukai (JP) 2019-01-23 EP claimed
EP-0914832-B1 THERAPEUTIC MATERIAL FOR PERIODONTOSIS KURARAY CO (JP) 2006-11-22 EP claimed
EP-0712635-B1 MEDICAL POLYMER GEL KURARAY CO (JP) 2003-05-02 EP claimed
US-5658592-A HEAT RESISTANCE, BIOCOMPATIBILITY, TRANSPARENCY; WOUND DRESSINGS KURARAY CO., LTD. (JP) 1997-08-19 US claimed
EP-3431140-B1 NERVE REGENERATION-INDUCING MATERIAL TAZUKE KOFUKAI (JP) 2024-03-27 EP disclosed
US-20210283304-A1 NERVE REGENERATION-INDUCING MATERIAL TAZUKE KOFUKAI (JP) 2021-09-16 US disclosed
US-11052174-B2 Nerve regeneration-inducing material Kofukai, Tazuke (JP) 2021-07-06 US disclosed
US-20200268931-A1 BRAIN DAMAGE RECOVERY MATERIAL TAZUKE KOFUKAI (JP) 2020-08-27 US disclosed
US-10307996-B2 Nano thin-film transfer sheet, method for manufacturing nano thin-film transfer sheet, and method for transferring nano thin-film layer into adherend HITACHI CHEMICAL COMPANY, LTD (JP) 2019-06-04 US disclosed
US-20050164980-A1 Hyaluronic acid modification product CHUGAI SEIYAKU KABUSHIKI KAISYA (JP) 2005-07-28 US disclosed
EP-1496037-A1 HYALURONIC ACID MODIFICATION PRODUCT CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2005-01-12 EP disclosed
US-6200595-B1 MIXTURE OF ANIONS AND CATIONS KURARAY CO., LTD. (JP) 2001-03-13 US disclosed
EP-0951914-A2 Medical adhesive KURARAY CO., LTD. (JP) 1999-10-27 EP disclosed
EP-0914832-A1 THERAPEUTIC MATERIAL FOR PERIODONTOSIS KURARAY CO., LTD. (JP) 1999-05-12 EP disclosed
US-5658592-A HEAT RESISTANCE, BIOCOMPATIBILITY, TRANSPARENCY; WOUND DRESSINGS KURARAY CO., LTD. (JP) 1997-08-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050164980-A1 Hyaluronic acid modification product CD44, HAAO, HAO1 DPP8 3674/4885DPP9 2989/4885DPP7 3224/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.