Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 10/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | RXRA | P19793 | 1/20 | 0.60 |
| ▸ | RXRB | P28702 | 1/20 | 0.60 |
| ▸ | RXRG | P48443 | 1/20 | 0.60 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.57 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.54 |
| ▸ | MMP12 | P39900 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3533619 | 0.89 | FFAR1 (0.87) | FFAR1RXRARXRBRXRGKEAP1 | |
| SCHEMBL14066660 | 0.89 | FFAR1 (0.87) | FFAR1RXRARXRBRXRGKEAP1 | |
| SCHEMBL8260837 | 0.88 | ALDH1A1 (0.77) | FFAR1ALDH1A1KEAP1FFAR4MMP12 | |
| SCHEMBL12126626 | 0.86 | ALDH1A1 (0.61) | FFAR1ALDH1A1RXRARXRBRXRG | |
| SCHEMBL10912165 | 0.85 | ALDH1A1 (0.77) | FFAR1ALDH1A1KEAP1FFAR4HSD17B10 | |
| SCHEMBL26604271 | 0.85 | RARB (0.64) | FFAR1ALDH1A1RXRARXRBHSD17B10 | |
| SCHEMBL23512465 | 0.84 | FFAR1 (0.71) | FFAR1ALDH1A1RXRARXRBRXRG | |
| SCHEMBL1510710 | 0.84 | FFAR1 (0.71) | FFAR1ALDH1A1RXRARXRBRXRG | |
| SCHEMBL1211561 | 0.83 | FFAR1 (1.00) | FFAR1RXRARXRBRXRGKEAP1 | |
| SCHEMBL8618654 | 0.83 | FFAR1 (1.00) | FFAR1RXRARXRBRXRGKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1408986-B1 | PROTEOMIMETIC COMPOUNDS AND METHODS | UNIV YALE (US) | 2008-09-24 | — | — | EP | disclosed |