Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | MAOA | P21397 | 2/20 | 0.55 |
| ▸ | MAOB | P27338 | 2/20 | 0.55 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29438821 | 0.87 | CHRM2 (0.70) | CHRM2SMN1; SMN2KDM4EMAOAMAOB | |
| SCHEMBL230222 | 0.87 | CHRM2 (0.70) | CHRM2SMN1; SMN2KDM4EMAOAMAOB | |
| Zinc Ion SCHEMBL30205248 | 0.85 | CHRM2 (0.68) | CHRM2SMN1; SMN2KDM4EMAOAMAOB | |
| Zinc Ion SCHEMBL30442739 | 0.85 | CHRM2 (0.68) | CHRM2SMN1; SMN2KDM4EMAOAMAOB | |
| SCHEMBL317984 | 0.85 | CHRM2 (0.68) | CHRM2SMN1; SMN2KDM4EMAOAMAOB | |
| SCHEMBL25211342 | 0.85 | CHRM2 (0.68) | CHRM2SMN1; SMN2KDM4EMAOAMAOB | |
| SCHEMBL18493706 | 0.85 | CHRM2 (0.68) | CHRM2SMN1; SMN2KDM4EMAOAMAOB | |
| SCHEMBL440639 | 0.84 | CHRM2 (0.68) | CHRM2SMN1; SMN2KDM4EMAOAMAOB | |
| SCHEMBL12831873 | 0.83 | SMN1; SMN2 (0.59) | CHRM2SMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL348655 | 0.83 | CHRM2 (0.78) | CHRM2SMN1; SMN2KDM4EMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1325910-B1 | ALIPHATIC NITROGENOUS FIVE-MEMBERED RING COMPOUNDS | MITSUBISHI TANABE PHARMA CORP (JP) | 2008-09-17 | — | — | EP | disclosed |