SCHEMBL348655

SCHEMBL348655

c1ccc(CNCCNCc2ccccn2)nc1

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.78
SIRT2 Q8IXJ6 1/20 0.60
MAOA P21397 2/20 0.59
MAOB P27338 2/20 0.59
ALOX15 P16050 3/20 0.58
KDM4E B2RXH2 2/20 0.58
ALDH1A1 P00352 2/20 0.58
SCN8A Q9UQD0 1/20 0.58
TSHR P16473 1/20 0.58
L3MBTL1 Q9Y468 1/20 0.58
SMN1; SMN2 Q16637 1/20 0.57
LMNA P02545 2/20 0.55
CYP1A2 P05177 2/20 0.55
HRH3 Q9Y5N1 1/20 0.53
CYP2D6 P10635 1/20 0.53
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
TAAR1 Q96RJ0 1/20 0.52
NPC1 O15118 1/20 0.51
RAB9A P51151 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3071526 0.98 CHRM2 (0.81) CHRM2SIRT2MAOAMAOBALOX15
SCHEMBL284677 0.98 CHRM2 (0.81) CHRM2SIRT2MAOAMAOBALOX15
Hydrochloric Acid SCHEMBL3626828 0.96 CHRM2 (0.79) CHRM2SIRT2MAOAMAOBALOX15
Hydrochloric Acid SCHEMBL9702944 0.96 CHRM2 (0.79) CHRM2SIRT2MAOAMAOBALOX15
SCHEMBL9777412 0.96 CHRM2 (0.79) CHRM2SIRT2MAOAMAOBALOX15
SCHEMBL9188072 0.92 CHRM2 (0.86) CHRM2SIRT2MAOAMAOBALOX15
SCHEMBL6231722 0.91 CHRM2 (0.85) CHRM2SIRT2MAOAMAOBALOX15
SCHEMBL16741961 0.91 CHRM2 (0.92) CHRM2SIRT2MAOAMAOBALOX15
SCHEMBL29438821 0.91 CHRM2 (0.70) CHRM2SIRT2MAOAMAOBALOX15
SCHEMBL230222 0.91 CHRM2 (0.70) CHRM2SIRT2MAOAMAOBALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3508473-B1 METHOD FOR PRODUCING CARBAMIC ACID ESTER AIST (JP) 2021-05-26 EP claimed
US-10752579-B2 Production method of carbamic acid ester NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2020-08-25 US claimed
EP-3672643-A2 MAGNETIC RESONANCE TOMOGRAPHY CONTRAST MEDIA, USE THEREOF FOR MEASURING TEMPERATURE AND METHOD FOR MEASURING TEMPERATURE Christian-Albrechts-Universität zu Kiel (DE) 2020-07-01 EP claimed
EP-3508473-A1 METHOD FOR PRODUCING CARBAMIC ACID ESTER National Institute of Advanced Industrial Science and Technology (JP) 2019-07-10 EP claimed
US-20190185420-A1 PRODUCTION METHOD OF CARBAMIC ACID ESTER NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2019-06-20 US claimed
US-5850086-A Iron complexes for bleach activation and stereospecific oxidation REGENTS OF THE UNIVERSITY OF MINNESOTA 1998-12-15 US claimed
WO-1997048710-A1 IRON COMPLEXES FOR BLEACH ACTIVATION AND STEREOSPECIFIC OXIDATION REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 1997-12-24 WO claimed
US-12607637-B2 Super-resolution morphology-correlated detection of labile zinc UNIVERSITY OF CINCINNATI (US) 2026-04-21 US disclosed
EP-4722190-A1 SUSTAINABLE SYNTHESIS OF A TERPENYLAMINE IN THE PRESENCE OF AT LEAST ONE ZINC-BASED PRECURSOR Nantes Université (FR) 2026-04-08 EP disclosed
EP-4158338-B1 SUPER-RESOLUTION MORPHOLOGY-CORRELATED DETECTION OF LABILE ZINC UNIV CINCINNATI (US) 2025-08-13 EP disclosed
CN-119462720-A Aminophenoxy transition metal complex and preparation method and application thereof 万华化学集团股份有限公司 2025-02-18 CN disclosed
EP-3426740-B1 METHOD OF PREPARING AN OXIDATIVELY CURABLE COATING FORMULATION MILLIKEN INDUSTRIALS LTD (GB) 2024-09-11 EP disclosed
CN-116874414-A Anionic and cationic p-type amino bisphenol oxy alkali metal complex, and preparation method and application thereof 华东理工大学 2023-10-13 CN disclosed
EP-1008645-A1 Detergent bleaching compositions UNILEVER PLC (GB) 2000-06-14 EP disclosed
US-5850086-A Iron complexes for bleach activation and stereospecific oxidation REGENTS OF THE UNIVERSITY OF MINNESOTA 1998-12-15 US disclosed
WO-1997048710-A1 IRON COMPLEXES FOR BLEACH ACTIVATION AND STEREOSPECIFIC OXIDATION REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 1997-12-24 WO disclosed
EP-0755925-A1 N,N'-di(aralkyl)-N,N'-di(2-azaaralkyl)alkylene-diamine derivatives and their use in pharmaceutical and cosmetic compositions L'OREAL (FR) 1997-01-29 EP disclosed
EP-0396435-B1 Polyaza derivatives and their metal complexes for use in the fixation of oxygen AIR LIQUIDE (FR) 1995-06-21 EP disclosed
EP-0396435-A1 Polyaza derivatives and their metal complexes for use in the fixation of oxygen L'AIR LIQUIDE, SOCIETE ANONYME POUR L'ETUDE ET L'EXPLOITATION DES PROCEDES GEORGES CLAUDE (FR) 1990-11-07 EP disclosed
WO-1990009987-A1 POLYNITROGENOUS DERIVATIVES AND THEIR METALLIC COMPLEXES WHICH CAN BE USED FOR OXYGEN FIXATION L'AIR LIQUIDE, SOCIETE ANONYME POUR L'ETUDE ET L'EXPLOITATION DES PROCEDES GEORGES CLAUDE (FR) 1990-09-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12607637-B2 Super-resolution morphology-correlated detection of labile zinc SARAF, TFEB, CHERP CHRM2 4387/4885SIRT2 936/4885MAOA 3729/4885
US-20190185420-A1 PRODUCTION METHOD OF CARBAMIC ACID ESTER CA2, CA7, CA4 CHRM2 174/4885SIRT2 570/4885MAOA 2769/4885
US-10752579-B2 Production method of carbamic acid ester CA2, CA7, CA4 CHRM2 174/4885SIRT2 570/4885MAOA 2769/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.