Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.38 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.38 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20889924 | 0.84 | CA2 (0.38) | SLC22A12ALDH1A1GAAKDM4EHPGD | |
| SCHEMBL1906819 | 0.80 | AR (0.43) | SLC22A12ALDH1A1GAAKDM4EHPGD | |
| SCHEMBL2418151 | 0.76 | SLC22A12 (0.55) | SLC22A12MAPTMAPK1CACNA1BAPBA1 | |
| SCHEMBL6017719 | 0.76 | KDM4E (0.50) | ALDH1A1GAAKDM4EHPGDL3MBTL1 | |
| SCHEMBL8118463 | 0.76 | AR (0.46) | SLC22A12ALDH1A1GAAKDM4EHPGD | |
| SCHEMBL880789 | 0.74 | ALDH1A1 (0.59) | ALDH1A1GAAKDM4EHPGDMAPT | |
| SCHEMBL11858460 | 0.73 | SLC22A12 (0.39) | SLC22A12ALDH1A1GAAKDM4EHPGD | |
| SCHEMBL11858450 | 0.73 | SLC22A12 (0.39) | SLC22A12ALDH1A1GAAKDM4EHPGD | |
| SCHEMBL7868327 | 0.73 | AR (0.46) | SLC22A12AR | |
| SCHEMBL2394925 | 0.73 | TSHR (0.40) | ALDH1A1GAAKDM4EHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1325910-B1 | ALIPHATIC NITROGENOUS FIVE-MEMBERED RING COMPOUNDS | MITSUBISHI TANABE PHARMA CORP (JP) | 2008-09-17 | — | — | EP | disclosed |
| US-7160877-B2 | Aliphatic nitrogen-containing 5-membered ring compound | TANABE SEIYAKU CO., LTD. (JP) | 2007-01-09 | — | — | US | disclosed |