Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.51 |
| ▸ | PNMT | P11086 | 5/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | TDP2 | O95551 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2246314 | 0.85 | DPP7 (0.53) | DPP7PNMTADRA2AMEN1MAPT | |
| SCHEMBL26640284 | 0.82 | DPP7 (0.48) | DPP7PNMTADRA2AMEN1MAPT | |
| SCHEMBL17797541 | 0.81 | PNMT (0.45) | DPP7PNMTADRA2AMEN1MAPT | |
| SCHEMBL21412716 | 0.81 | HRH3 (0.55) | DPP7MEN1MAPTKMT2ALMNA | |
| SCHEMBL17797625 | 0.81 | DPP7 (0.44) | DPP7PNMTADRA2AMEN1MAPT | |
| SCHEMBL1950140 | 0.81 | GRIN1 (0.57) | MAPTGRIN1GRIN2B | |
| SCHEMBL1997187 | 0.80 | MAPT (0.50) | ADRA2AMEN1MAPTKMT2ALMNA | |
| SCHEMBL29383310 | 0.80 | DPP7 (0.43) | DPP7PNMTADRA2AMEN1MAPT | |
| Hydrochloric Acid SCHEMBL7511818 | 0.79 | GRIN1 (0.56) | MAPTGRIN1GRIN2B | |
| SCHEMBL29945643 | 0.79 | DPP7 (0.50) | DPP7PNMTADRA2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1325910-B1 | ALIPHATIC NITROGENOUS FIVE-MEMBERED RING COMPOUNDS | MITSUBISHI TANABE PHARMA CORP (JP) | 2008-09-17 | — | — | EP | disclosed |