Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.50 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.50 |
| ▸ | PNMT | P11086 | 6/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | TDP2 | O95551 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL324724 | 0.88 | ADRA2A (0.51) | SIRT6PNMTADRA2AMEN1MAPT | |
| SCHEMBL29558059 | 0.88 | ADRA2A (0.51) | SIRT6PNMTADRA2AMEN1MAPT | |
| SCHEMBL17797602 | 0.88 | DPP7 (0.47) | DPP7SIRT6PNMTADRA2AADRA2B | |
| SCHEMBL29990004 | 0.86 | MAOA (0.50) | SIRT6PNMTADRA2AMEN1MAPT | |
| Hydrochloric Acid SCHEMBL7832321 | 0.86 | ADRA2A (0.50) | SIRT6PNMTADRA2AMEN1MAPT | |
| SCHEMBL20232216 | 0.86 | MAOA (0.50) | SIRT6PNMTADRA2AMEN1MAPT | |
| SCHEMBL1952321 | 0.85 | LMNA (0.50) | DPP7SIRT6PNMTADRA2AMEN1 | |
| SCHEMBL18387886 | 0.82 | TDP2 (0.53) | MEN1MAPTKMT2ALMNARAB9A | |
| SCHEMBL2246314 | 0.81 | DPP7 (0.53) | DPP7PNMTADRA2AADRA2BADRA2C | |
| SCHEMBL17797505 | 0.81 | DPP7 (0.47) | DPP7PNMTADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115109012-A | Benzyl arylamine aldehyde dehydrogenase agonist, and synthesis method and application thereof | 中国人民解放军海军军医大学 | 2022-09-27 | — | — | CN | disclosed |