Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 11/20 | 0.49 |
| ▸ | HTR2A | P28223 | 9/20 | 0.49 |
| ▸ | HTR1A | P08908 | 7/20 | 0.49 |
| ▸ | HTR2C | P28335 | 7/20 | 0.48 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31016920 | 0.82 | HDAC3 (0.65) | HDAC3HDAC1HDAC2DRD3HTR2A | |
| SCHEMBL4078388 | 0.82 | KDM4E (0.56) | ALDH1A1KDM4EHDAC3HDAC1HDAC2 | |
| SCHEMBL14875993 | 0.80 | EGLN1 (0.57) | ALDH1A1KDM4EHDAC3HDAC1HDAC2 | |
| SCHEMBL16307678 | 0.79 | HDAC3 (0.57) | HDAC3HDAC1HDAC2DRD3HTR2A | |
| SCHEMBL27833508 | 0.78 | HIF1A (0.64) | MEN1KMT2ACYP1A2CYP3A4EGLN1 | |
| SCHEMBL5100085 | 0.78 | EGLN1 (0.52) | ALDH1A1HDAC3HDAC1HDAC2DRD3 | |
| SCHEMBL5926434 | 0.78 | EGLN1 (0.67) | HDAC3HDAC1HDAC2DRD3HTR2A | |
| SCHEMBL445261 | 0.78 | NPC1 (0.52) | MEN1KMT2ASMN1; SMN2HDAC3HDAC1 | |
| SCHEMBL29078735 | 0.77 | KMT2A (0.50) | MEN1KMT2AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL14067675 | 0.77 | MEN1 (0.56) | MEN1KMT2AALDH1A1KDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080227806-A1 | Novel Drugs for Dementia | AMERICAN LIFE SCIENCE PHARMACEUTICALS (US) | 2008-09-18 | — | — | US | disclosed |
| US-20080227806-A1 | Novel Drugs for Dementia | AMERICAN LIFE SCIENCE PHARMACEUTICALS (US) | 2008-09-18 | — | — | US | disclosed |
| WO-2007038772-A1 | NOVEL DRUGS FOR DEMENTIA | AMERICAN LIFE SCIENCE PHARMACEUTICALS (US) | 2007-04-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080227806-A1 | Novel Drugs for Dementia | CTSS, PRSS1, CBS | MEN1 2586/4885KMT2A 3879/4885ALDH1A1 2533/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.