Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | CTSS | P25774 | 3/20 | 0.49 |
| ▸ | CTSL | P07711 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14025827 | 0.84 | KDM4E (0.59) | MEN1KMT2ARAB9AHDAC1HDAC6 | |
| SCHEMBL4922041 | 0.81 | KMT2A (0.52) | MEN1KMT2AHDAC1HDAC6HDAC3 | |
| SCHEMBL17117491 | 0.78 | MEN1 (0.84) | MEN1KMT2ARAB9AHDAC1HDAC6 | |
| SCHEMBL4741844 | 0.78 | KMT2A (0.65) | MEN1KMT2ARAB9AHDAC1HDAC6 | |
| SCHEMBL39945 | 0.78 | KDM4E (0.56) | KDM4ELMNASIGMAR1TMEM97ACHE | |
| SCHEMBL3655080 | 0.77 | MEN1 (0.73) | MEN1KMT2ARAB9AKDM4EALDH1A1 | |
| SCHEMBL4914918 | 0.76 | POLB (0.54) | MEN1KMT2ARAB9AHDAC1HDAC6 | |
| SCHEMBL14025829 | 0.76 | HDAC1 (0.46) | MEN1KMT2AHDAC1HDAC6HDAC3 | |
| SCHEMBL17117334 | 0.76 | KMT2A (0.85) | MEN1KMT2ARAB9AKDM4EALDH1A1 | |
| SCHEMBL4926596 | 0.74 | ACHE (0.46) | MEN1KMT2ARAB9AHDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008109154-A1 | CHEMOKINE RECEPTOR MODULATORS | ALTIRIS THERAPEUTICS, INC. (US) | 2008-09-12 | — | — | WO | disclosed |