Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 8/20 | 0.37 |
| ▸ | MAPT | P10636 | 7/20 | 0.37 |
| ▸ | MEN1 | O00255 | 6/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.37 |
| ▸ | NOX1 | Q9Y5S8 | 5/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14128490 | 0.73 | GAA (0.39) | GAAMAPTMEN1KMT2ANOX1 | |
| SCHEMBL18830891 | 0.68 | JAK2 (0.36) | GAAALOX15NPSR1HSD17B10 | |
| SCHEMBL10838548 | 0.67 | HSD17B10 (0.58) | GAAMAPTMEN1KMT2ANOX1 | |
| SCHEMBL4510651 | 0.66 | GAA (0.52) | GAAMAPTMEN1KMT2ANOX1 | |
| SCHEMBL8556056 | 0.66 | GAA (0.46) | GAAMAPTMEN1KMT2ANOX1 | |
| SCHEMBL10840315 | 0.65 | MAOB (0.46) | MAPTMEN1KMT2ACYP1A2BCHE | |
| SCHEMBL21082440 | 0.62 | GAA (0.35) | GAAMAPTMEN1KMT2ANOX1 | |
| SCHEMBL8563069 | 0.61 | MEN1 (0.43) | GAAMAPTMEN1KMT2ANOX1 | |
| SCHEMBL8561569 | 0.61 | MEN1 (0.47) | GAAMAPTMEN1KMT2ANOX1 | |
| SCHEMBL11319550 | 0.59 | NOX1 (0.58) | GAAMAPTMEN1KMT2ANOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008108842-A1 | LISOFYLLINE ANALOGS AND METHODS FOR USE | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2008-09-12 | — | — | WO | disclosed |