Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 14/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 14/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9930117 | 0.69 | CYP11B2 (0.48) | CYP11B2CYP11B1CYP1A2CYP17A1CYP19A1 | |
| SCHEMBL14069832 | 0.69 | CYP11B2 (0.48) | CYP11B2CYP11B1CYP1A2CYP17A1CYP19A1 | |
| SCHEMBL14506746 | 0.64 | MKNK1 (0.61) | CYP11B2CYP11B1CYP1A2CYP17A1CYP19A1 | |
| Hydrochloric Acid SCHEMBL7811303 | 0.64 | GRM2 (0.44) | GRM2 | |
| Hydrochloric Acid SCHEMBL8513744 | 0.64 | GRM2 (0.44) | GRM2 | |
| SCHEMBL28857629 | 0.63 | ALDH1A1 (0.61) | CYP11B2CYP11B1CYP1A2CYP17A1CYP19A1 | |
| SCHEMBL29898220 | 0.63 | ALDH1A1 (0.61) | CYP11B2CYP11B1CYP1A2CYP17A1CYP19A1 | |
| SCHEMBL1119366 | 0.62 | CYP11B2 (1.00) | CYP11B2CYP11B1CYP1A2CYP17A1CYP19A1 | |
| SCHEMBL769062 | 0.61 | CYP11B1 (0.78) | CYP11B2CYP11B1CYP1A2CYP17A1CYP19A1 | |
| SCHEMBL28011974 | 0.61 | MKNK1 (0.50) | CYP11B2CYP11B1CYP1A2CYP17A1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008108988-A1 | ANTIMICROBIAL HETEROCYCLIC COMPOUNDS FOR TREATMENT OF BACTERIAL INFECTIONS | MICURX PHARMACEUTICALS, INC. (US) | 2008-09-12 | — | — | WO | disclosed |