Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 7/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14029915 | 0.83 | SLC2A1 (0.41) | HDAC1HDAC8HDAC6SLC2A1 | |
| SCHEMBL14005000 | 0.81 | NPC1 (0.45) | HDAC1HDAC8HDAC6SYKPKM | |
| SCHEMBL13879819 | 0.74 | PKM (0.52) | HDAC1HDAC8HDAC6SYKPKM | |
| SCHEMBL13879795 | 0.69 | KDM4E (0.50) | HDAC1HDAC8HDAC6PKM | |
| Msx-122 SCHEMBL10054965 | 0.66 | CXCR4 (0.61) | HDAC1HDAC8HDAC6 | |
| SCHEMBL15719106 | 0.66 | RAB9A (0.54) | PKM | |
| SCHEMBL15719105 | 0.66 | RAB9A (0.54) | PKM | |
| SCHEMBL13891925 | 0.65 | SYK (0.47) | HDAC1HDAC6SYKPKM | |
| SCHEMBL14005153 | 0.65 | PKM (0.61) | SYKPKM | |
| SCHEMBL14025742 | 0.65 | NAMPT (0.52) | SYKPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008112156-A1 | CHEMOKINE RECEPTOR MODULATORS | ALTIRIS THERAPEUTICS (US) | 2008-09-18 | — | — | WO | disclosed |