Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SUCNR1 | Q9BXA5 | 10/20 | 0.52 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.47 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.45 |
| ▸ | FEN1 | P39748 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14070566 | 0.86 | SUCNR1 (0.48) | SUCNR1S1PR4ALDH1A1MAPT | |
| SCHEMBL14069943 | 0.85 | S1PR4 (0.49) | SUCNR1S1PR4KDM4ECYP1A2CYP2C19 | |
| SCHEMBL14069946 | 0.81 | CPT2 (0.53) | SUCNR1PTPN11 | |
| SCHEMBL13410032 | 0.81 | TAS1R3 (0.59) | ALDH1A1HPGDLMNAMAPTSMN1; SMN2 | |
| SCHEMBL13444465 | 0.81 | HPGD (0.43) | ALDH1A1HPGDLMNAMAPTSMN1; SMN2 | |
| SCHEMBL26264278 | 0.79 | SUCNR1 (0.72) | SUCNR1ERCC5FEN1ALDH1A1HPGD | |
| SCHEMBL13409928 | 0.79 | ALDH1A1 (0.51) | ALDH1A1HPGDKDM4ELMNAMAPT | |
| SCHEMBL13409966 | 0.78 | ALDH1A1 (0.48) | ALDH1A1HPGDLMNAMAPTSMN1; SMN2 | |
| SCHEMBL13444646 | 0.78 | ALDH1A1 (0.43) | ALDH1A1HPGDKDM4ELMNACYP1A2 | |
| SCHEMBL14069885 | 0.78 | NPC1 (0.51) | ALDH1A1LMNAMAPTMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008109991-A1 | INHIBITORS OF CARNITINE PALMITOYLTRANSFERASE AND TREATING CANCER | UNIVERSITY HEALTH NETWORK (CA) | 2008-09-18 | — | — | WO | disclosed |