Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | MLNR | O43193 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | NPY1R | P25929 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14070987 | 0.87 | STS (0.39) | FFAR1CHRNA7AKR1B1CHRM1MLNR | |
| SCHEMBL14071024 | 0.85 | STS (0.38) | FFAR1CHRNA7AKR1B1CHRM1MLNR | |
| SCHEMBL14079534 | 0.84 | STS (0.33) | CHRNA7STS | |
| SCHEMBL14071455 | 0.81 | TLR4 (0.32) | CHRNA7STS | |
| SCHEMBL14071481 | 0.80 | TLR4 (0.34) | CHRNA7STS | |
| SCHEMBL14071454 | 0.80 | STS (0.33) | CHRNA7STS | |
| SCHEMBL14070963 | 0.80 | STS (0.46) | FFAR1CHRNA7AKR1B1CHRM1MLNR | |
| SCHEMBL14070908 | 0.79 | STS (0.48) | FFAR1CHRNA7AKR1B1CHRM1MLNR | |
| SCHEMBL14071482 | 0.79 | TLR4 (0.33) | STS | |
| SCHEMBL14071450 | 0.79 | PKM (0.31) | STS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7429411-B2 | Chroman compound, liquid crystal composition including the compound and liquid crystal display element including the liquid crystal composition | CHISSO PETROCHEMICAL CORPORATION (JP) | 2008-09-30 | — | — | US | disclosed |
| US-7429411-B2 | Chroman compound, liquid crystal composition including the compound and liquid crystal display element including the liquid crystal composition | CHISSO PETROCHEMICAL CORPORATION (JP) | 2008-09-30 | — | — | US | disclosed |
| US-7429411-B2 | Chroman compound, liquid crystal composition including the compound and liquid crystal display element including the liquid crystal composition | CHISSO PETROCHEMICAL CORPORATION (JP) | 2008-09-30 | — | — | US | disclosed |
| EP-1491612-B1 | Chroman compound, liquid crystal composition including the compound and liquid crystal display element including the liquid crystal composition | CHISSO PETROCHEMICAL CORP (JP) | 2006-10-18 | — | — | EP | disclosed |
| US-20050247910-A1 | Chroman compound, liquid crystal composition including the compound and liquid crystal display element including the liquid crystal composition | JNC PETROCHEMICAL CORPORATION (JP) | 2005-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050247910-A1 | Chroman compound, liquid crystal composition including the compound and liquid crystal display element including the liquid crystal composition | RB1, RCC1, CDYL | HTR1D 193/4885HTR1B 1512/4885FFAR1 3021/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.