Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 3/20 | 0.38 |
| ▸ | EDNRB | P24530 | 1/20 | 0.38 |
| ▸ | EDNRA | P25101 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11326904 | 0.85 | BCL2 (0.53) | BCL2PTGS2TAAR1TP53MAPKAPK2 | |
| SCHEMBL9007144 | 0.81 | BCL2 (0.65) | BCL2PTGS2TAAR1TP53 | |
| SCHEMBL29924029 | 0.81 | BCL2 (0.65) | BCL2PTGS2TAAR1TP53 | |
| SCHEMBL14071659 | 0.78 | TP53 (0.43) | TAAR1TP53 | |
| SCHEMBL14979414 | 0.78 | MAOA (0.48) | TAAR1 | |
| SCHEMBL13350170 | 0.78 | HSD17B1 (0.39) | TAAR1 | |
| SCHEMBL18371214 | 0.76 | MEN1 (0.48) | TAAR1 | |
| SCHEMBL18371221 | 0.76 | MEN1 (0.48) | TAAR1 | |
| SCHEMBL8046780 | 0.76 | — | — | |
| SCHEMBL10243468 | 0.76 | MAOA (0.59) | BCL2TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008116156-A2 | METHODS AND COMPOSITIONS FOR TREATING DISEASES AND CONDITIONS ASSOCIATED WITH MITOCHONDRIAL FUNCTION | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2008-09-25 | — | — | WO | disclosed |