Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 4/20 | 0.41 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.41 |
| ▸ | GPR17 | Q13304 | 2/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 6/20 | 0.36 |
| ▸ | P2RX2 | Q9UBL9 | 4/20 | 0.36 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.36 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.36 |
| ▸ | NT5E | P21589 | 1/20 | 0.33 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.33 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL264096 | 0.84 | GPR17 (0.43) | P2RY1P2RY2GPR17P2RX3P2RX2 | |
| SCHEMBL13877182 | 0.83 | P2RY2 (0.41) | P2RY1P2RY2GPR17P2RX3P2RX2 | |
| SCHEMBL2610998 | 0.78 | P2RX3 (0.49) | P2RY1P2RY2GPR17P2RX3P2RX2 | |
| SCHEMBL264673 | 0.74 | P2RY1 (0.35) | P2RY1P2RY2P2RY12 | |
| SCHEMBL264779 | 0.72 | P2RX3 (0.47) | P2RY1P2RY2P2RX3P2RX2P2RX4 | |
| SCHEMBL280492 | 0.72 | P2RX3 (0.46) | P2RY1P2RY2P2RX3P2RX2P2RX4 | |
| SCHEMBL280534 | 0.67 | CA12 (0.36) | — | |
| SCHEMBL24320810 | 0.67 | P2RY1 (0.57) | P2RY1P2RY2GPR17P2RX3P2RX2 | |
| SCHEMBL264655 | 0.65 | ADORA3 (0.40) | — | |
| SCHEMBL21283049 | 0.63 | P2RY1 (0.53) | P2RY1P2RY2GPR17P2RX3P2RX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7429571-B2 | Therapeutic furopyrimidines and thienopyrimidines | BIOCRYST PHARMACEUTICALS, INC. (US) | 2008-09-30 | — | — | US | disclosed |