Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UCHL1 | P09936 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 6/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAT2A | P31153 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL332939 | 0.93 | UCHL1 (0.38) | UCHL1MEN1KMT2AMAPTHIF1A | |
| SCHEMBL3005796 | 0.84 | UCHL1 (0.40) | UCHL1MAPTHIF1ATP53SMN1; SMN2 | |
| SCHEMBL3013557 | 0.83 | UCHL1 (0.39) | UCHL1MEN1KMT2AMAPTHIF1A | |
| SCHEMBL3579153 | 0.83 | UCHL1 (0.41) | UCHL1MEN1KMT2AMAPTHIF1A | |
| SCHEMBL3007510 | 0.82 | KMT2A (0.44) | MEN1KMT2AMAPTHIF1ATP53 | |
| SCHEMBL3002124 | 0.81 | UCHL1 (0.37) | UCHL1MAPTHIF1ATP53SMN1; SMN2 | |
| SCHEMBL333693 | 0.77 | MAPT (0.43) | MEN1KMT2AMAPTTP53SMN1; SMN2 | |
| SCHEMBL334136 | 0.72 | PTGES (0.53) | MAPTTP53SMN1; SMN2THRBPPARG | |
| SCHEMBL30633802 | 0.70 | UCHL1 (0.39) | UCHL1MAPTHIF1AALDH1A1PKM | |
| SCHEMBL3570481 | 0.68 | UCHL1 (0.39) | UCHL1MEN1KMT2AMAPTHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1841735-B1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2011-03-09 | — | — | EP | disclosed |