Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 7/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | TSHR | P16473 | 4/20 | 0.58 |
| ▸ | CASP1 | P29466 | 4/20 | 0.58 |
| ▸ | CASP7 | P55210 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2524666 | 0.90 | CFTR (0.65) | CFTRKDM4EKMT2AALDH1A1TSHR | |
| SCHEMBL12213255 | 0.87 | CFTR (0.69) | CFTRKDM4EKMT2AALDH1A1TSHR | |
| SCHEMBL14235358 | 0.82 | CFTR (1.00) | CFTRKDM4EKMT2AALDH1A1TSHR | |
| SCHEMBL5016780 | 0.79 | KDM4E (0.71) | CFTRKDM4EKMT2AALDH1A1TSHR | |
| SCHEMBL14073364 | 0.77 | ALDH1A1 (0.70) | CFTRKDM4EKMT2AALDH1A1TSHR | |
| SCHEMBL5016782 | 0.76 | KDM4E (0.73) | CFTRKDM4EKMT2AALDH1A1TSHR | |
| SCHEMBL14235359 | 0.75 | CFTR (1.00) | CFTRKDM4EKMT2AALDH1A1TSHR | |
| SCHEMBL12043094 | 0.75 | KDM4E (0.85) | CFTRKDM4EKMT2AALDH1A1TSHR | |
| SCHEMBL12043100 | 0.75 | MEN1 (0.69) | CFTRKDM4EKMT2AALDH1A1TSHR | |
| SCHEMBL14235249 | 0.75 | CFTR (1.00) | CFTRKDM4EKMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080234253-A1 | Methods and Compositons for Stimulating Neurogenesis and Inhibiting Neuronal Degeneration | NEURONASCENT, INC. (US) | 2008-09-25 | — | — | US | disclosed |
| US-20080234253-A1 | Methods and Compositons for Stimulating Neurogenesis and Inhibiting Neuronal Degeneration | NEURONASCENT, INC. (US) | 2008-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080234253-A1 | Methods and Compositons for Stimulating Neurogenesis and Inhibiting Neuronal Degeneration | DCX, BDNF, GAP43 | CFTR 3437/4885KDM4E 4443/4885KMT2A 4557/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.