Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.54 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | RARB | P10826 | 2/20 | 0.40 |
| ▸ | RARG | P13631 | 2/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14073395 | 0.87 | SRD5A2 (0.50) | SIRT1SRD5A2NPC1RAB9APDK2 | |
| SCHEMBL1637360 | 0.83 | ALDH1A1 (0.53) | SRD5A2RAB9ASMN1; SMN2CNR1CNR2 | |
| SCHEMBL16419700 | 0.82 | SRD5A2 (0.45) | SRD5A2NPC1RAB9APDK2ALDH1A1 | |
| SCHEMBL14073390 | 0.81 | PDK2 (0.44) | NPC1RAB9ASMN1; SMN2PDK2ALDH1A1 | |
| SCHEMBL13045515 | 0.80 | PDK2 (0.52) | PDK2RARBRARGRXRARXRB | |
| SCHEMBL1553113 | 0.79 | PDK2 (0.53) | SIRT1SRD5A2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1552805 | 0.79 | PDK2 (0.53) | SIRT1SRD5A2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14073423 | 0.78 | PDK2 (0.38) | NPC1RAB9APDK2MAPT | |
| SCHEMBL20036916 | 0.77 | PDK2 (0.41) | NPC1RAB9ASMN1; SMN2PDK2ALDH1A1 | |
| SCHEMBL10946728 | 0.76 | SRD5A2 (0.83) | SIRT1SRD5A2NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1883688-B1 | COMPOUNDS FOR ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2018-04-11 | — | — | EP | disclosed |
| US-9461249-B2 | Compounds for organic electronic devices | MERCK PATENT GMBH (DE) | 2016-10-04 | — | — | US | disclosed |
| US-9461249-B2 | Compounds for organic electronic devices | MERCK PATENT GMBH (DE) | 2016-10-04 | — | — | US | disclosed |
| US-20150031896-A1 | COMPOUNDS FOR ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2015-01-29 | — | — | US | disclosed |
| US-20150031896-A1 | COMPOUNDS FOR ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2015-01-29 | — | — | US | disclosed |
| US-8852756-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2014-10-07 | — | — | US | disclosed |
| US-8852756-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2014-10-07 | — | — | US | disclosed |
| US-20080220285-A1 | Derivatives of fused aromatic systems; sublimation stability; easy to purify due to better solubilty; easy reproducibility because do not form isomers; high efficiency and high stability on use in organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2008-09-11 | — | — | US | disclosed |
| US-20080220285-A1 | Derivatives of fused aromatic systems; sublimation stability; easy to purify due to better solubilty; easy reproducibility because do not form isomers; high efficiency and high stability on use in organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080220285-A1 | Derivatives of fused aromatic systems; sublimation stability; easy to purify due to better solubilty; easy reproducibility because do not form isomers; high efficiency and high stability on use in organic electroluminescent devices | TYR, DDT, PAH | SIRT1 1712/4885SRD5A2 731/4885NPC1 1783/4885 |
| US-20150031896-A1 | COMPOUNDS FOR ORGANIC ELECTRONIC DEVICES | TYR, TOE1, GPX1 | SIRT1 2185/4885SRD5A2 1536/4885NPC1 2095/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.