Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 3/20 | 0.50 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.48 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 1/20 | 0.39 |
| ▸ | RARG | P13631 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16419700 | 0.95 | SRD5A2 (0.45) | SRD5A2PDK2CYP2C8CES2CES1 | |
| SCHEMBL14073419 | 0.87 | SIRT1 (0.54) | SRD5A2PDK2NPC1RAB9ARARB | |
| SCHEMBL14073390 | 0.83 | PDK2 (0.44) | PDK2CES2CES1NPC1RAB9A | |
| SCHEMBL1637360 | 0.81 | ALDH1A1 (0.53) | SRD5A2PDK2CES2CES1RAB9A | |
| SCHEMBL13045515 | 0.78 | PDK2 (0.52) | PDK2RARBRARGRXRARXRB | |
| SCHEMBL20036916 | 0.78 | PDK2 (0.41) | PDK2CES2CES1NPC1RAB9A | |
| SCHEMBL20036915 | 0.77 | PDK2 (0.40) | PDK2CES2CES1NPC1RAB9A | |
| SCHEMBL648641 | 0.75 | SRD5A2 (0.83) | SRD5A2CYP2C8CES2CES1NPC1 | |
| SCHEMBL14073311 | 0.75 | PDK2 (0.49) | PDK2RARBRARGRXRARXRB | |
| SCHEMBL14073388 | 0.75 | CNR2 (0.50) | PDK2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1883688-B1 | COMPOUNDS FOR ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2018-04-11 | — | — | EP | disclosed |
| US-8852756-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2014-10-07 | — | — | US | disclosed |
| US-8852756-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2014-10-07 | — | — | US | disclosed |
| US-20080220285-A1 | Derivatives of fused aromatic systems; sublimation stability; easy to purify due to better solubilty; easy reproducibility because do not form isomers; high efficiency and high stability on use in organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2008-09-11 | — | — | US | disclosed |
| US-20080220285-A1 | Derivatives of fused aromatic systems; sublimation stability; easy to purify due to better solubilty; easy reproducibility because do not form isomers; high efficiency and high stability on use in organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080220285-A1 | Derivatives of fused aromatic systems; sublimation stability; easy to purify due to better solubilty; easy reproducibility because do not form isomers; high efficiency and high stability on use in organic electroluminescent devices | TYR, DDT, PAH | SRD5A2 731/4885PDK2 519/4885CYP2C8 520/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.